A leg-up on the career ladder: meet our new research Fellows


Our new researchers with some of our funding team

It’s that time of year again – a time to welcome some new researchers to Cancer Research UK. This group of talented scientists impressed our funding committees with their pioneering ideas, talent and commitment to helping us beat cancer sooner.

The new Fellows – as they’re called – are still on the early rungs of their career ladder, and we’re very pleased to be helping them on their way.

If we’re to carry on making progress against cancer, we need this bright new generation of researchers to spark new ways of thinking, and do the research that will take us nearer to finding cures for all types of the disease.

Here’s a brief introduction to our new researchers, and we look forward to hearing about their exciting work in the future.

Click to view slideshow.
  • Dr Paul Huang from the ICR in London is focusing on how lung cancer cells ‘rewire’ their internal communications system to become resistant to treatment.
  • Dr Trevor Graham, based at Barts Cancer Institute in London, is looking for genetic changes that allow bowel cancer to become resistant to therapy. Using computers to map these changes, his goal is being able to predict how cancer cells will adapt to treatment, to see if better combinations of drugs could stop cancer coming back.
  • At UCL in London, Dr Sophie Acton is studying cells surrounding tumours that could be shielding them from the immune system. Understanding how neighbouring cells ‘talk to’ immune cells could provide an opportunity to remove these barriers and help immune cells attack tumours.
  • Dr Ross Chapman, based in Oxford, is investigating one of the most-well known genes in cancer – p53. Mistakes in p53 play a key role in cancer development, but Dr Chapman is investigating some of the molecules that p53 talks to, to find out whether faults in these molecules can also drive cancer.
  • Up at the Beatson Institute in Glasgow, Dr Oliver Maddocks is studying how cancer cells turn nutrients into the energy and building blocks they need to grow. Limiting the amount of certain nutrients might help slow the growth of tumours or make them more susceptible to particular drugs.
  • Dr Kevin Myant in Edinburgh is investigating a faulty molecule, called RAC1, in bowel cancer. He thinks a faulty version made by bowel cancer cells is too active. The research could lead to new treatments that block this faulty molecule.
  • Dr Geoff Higgins, based at Oxford, is researching ways to make cancer cells more sensitive to radiotherapy, potentially boosting how effective this treatment is.
  • In London, Dr Michelle Lockley is working with viruses that have been genetically engineered to destroy cancer cells. She is looking at whether combining these viruses with various cancer drugs makes them more effective.
  • Dr Matthew Hoare in Cambridge is studying the way faulty cells often ‘go to sleep’ as one of our body’s defence mechanisms against cancer. His team is finding out whether these ‘sleeping’ cells could be an early warning sign that cancer might develop, and could help doctors identify people at higher risk.
  • And in Glasgow, Dr Imran Ahmad is a surgeon specialising in prostate cancer. He’s carrying out lab research to investigate genetic changes that happen in prostate cells as the disease becomes more advanced and becomes resistant to treatment.

Emma



from Cancer Research UK - Science blog http://ift.tt/1NEH5Sv
Our new researchers with some of our funding team

It’s that time of year again – a time to welcome some new researchers to Cancer Research UK. This group of talented scientists impressed our funding committees with their pioneering ideas, talent and commitment to helping us beat cancer sooner.

The new Fellows – as they’re called – are still on the early rungs of their career ladder, and we’re very pleased to be helping them on their way.

If we’re to carry on making progress against cancer, we need this bright new generation of researchers to spark new ways of thinking, and do the research that will take us nearer to finding cures for all types of the disease.

Here’s a brief introduction to our new researchers, and we look forward to hearing about their exciting work in the future.

Click to view slideshow.
  • Dr Paul Huang from the ICR in London is focusing on how lung cancer cells ‘rewire’ their internal communications system to become resistant to treatment.
  • Dr Trevor Graham, based at Barts Cancer Institute in London, is looking for genetic changes that allow bowel cancer to become resistant to therapy. Using computers to map these changes, his goal is being able to predict how cancer cells will adapt to treatment, to see if better combinations of drugs could stop cancer coming back.
  • At UCL in London, Dr Sophie Acton is studying cells surrounding tumours that could be shielding them from the immune system. Understanding how neighbouring cells ‘talk to’ immune cells could provide an opportunity to remove these barriers and help immune cells attack tumours.
  • Dr Ross Chapman, based in Oxford, is investigating one of the most-well known genes in cancer – p53. Mistakes in p53 play a key role in cancer development, but Dr Chapman is investigating some of the molecules that p53 talks to, to find out whether faults in these molecules can also drive cancer.
  • Up at the Beatson Institute in Glasgow, Dr Oliver Maddocks is studying how cancer cells turn nutrients into the energy and building blocks they need to grow. Limiting the amount of certain nutrients might help slow the growth of tumours or make them more susceptible to particular drugs.
  • Dr Kevin Myant in Edinburgh is investigating a faulty molecule, called RAC1, in bowel cancer. He thinks a faulty version made by bowel cancer cells is too active. The research could lead to new treatments that block this faulty molecule.
  • Dr Geoff Higgins, based at Oxford, is researching ways to make cancer cells more sensitive to radiotherapy, potentially boosting how effective this treatment is.
  • In London, Dr Michelle Lockley is working with viruses that have been genetically engineered to destroy cancer cells. She is looking at whether combining these viruses with various cancer drugs makes them more effective.
  • Dr Matthew Hoare in Cambridge is studying the way faulty cells often ‘go to sleep’ as one of our body’s defence mechanisms against cancer. His team is finding out whether these ‘sleeping’ cells could be an early warning sign that cancer might develop, and could help doctors identify people at higher risk.
  • And in Glasgow, Dr Imran Ahmad is a surgeon specialising in prostate cancer. He’s carrying out lab research to investigate genetic changes that happen in prostate cells as the disease becomes more advanced and becomes resistant to treatment.

Emma



from Cancer Research UK - Science blog http://ift.tt/1NEH5Sv

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