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How FOX treats Christians vs. Muslims [Greg Laden's Blog]

Not the same.

Muslims must take the blame for all things done by anyone linked to an extreme Islamic group or ideology. Christians have nothing to do with anything, they were just standing there minding their own beeswax.

The video below was fixed by Media Matters for America thusly:

In a notably hypocritical segment on Fox & Friends, the hosts and their guest, David Brody of the Christian Broadcasting Network, attacked media outlets that called on Christian leaders to denounce white supremacy and the recent violence in Charlottesville, VA. Fox & Friends highlighted articles that noted that many white evangelical leaders have been silent since white supremacists in Charlottesville attacked counter-protesters on August 12 and that historically many Christians and Christian organizations have enabled systemic racism, from slavery to Jim Crow and into the current era. Co-host Pete Hegseth asked why the articles were “trying to make that link” and “rush[ing] to say” that “pastors or churches … are to blame.” Fellow co-host Abby Huntsman said that “people are pointing fingers” and “you have some journalists that are blaming white Christians.” And Brody claimed that “the fix is in, if you will, against evangelical Christians, white evangelical Christians in this country.”



from ScienceBlogs http://ift.tt/2vGHnqk

Not the same.

Muslims must take the blame for all things done by anyone linked to an extreme Islamic group or ideology. Christians have nothing to do with anything, they were just standing there minding their own beeswax.

The video below was fixed by Media Matters for America thusly:

In a notably hypocritical segment on Fox & Friends, the hosts and their guest, David Brody of the Christian Broadcasting Network, attacked media outlets that called on Christian leaders to denounce white supremacy and the recent violence in Charlottesville, VA. Fox & Friends highlighted articles that noted that many white evangelical leaders have been silent since white supremacists in Charlottesville attacked counter-protesters on August 12 and that historically many Christians and Christian organizations have enabled systemic racism, from slavery to Jim Crow and into the current era. Co-host Pete Hegseth asked why the articles were “trying to make that link” and “rush[ing] to say” that “pastors or churches … are to blame.” Fellow co-host Abby Huntsman said that “people are pointing fingers” and “you have some journalists that are blaming white Christians.” And Brody claimed that “the fix is in, if you will, against evangelical Christians, white evangelical Christians in this country.”



from ScienceBlogs http://ift.tt/2vGHnqk

Worth reading: Methadone, police violence, and taking children from their parents [The Pump Handle]

A few of the recent pieces I recommend reading:

Larissa MacFarquhar in the New Yorker: When Should a Child Be Taken from His Parents?

Brian Rinker at STAT: 32 churches and no methadone clinic: struggling with addiction in an opioid ‘treatment desert’

Renee Bracey Sherman in the New York Times: The Right to (Black) Life

Brianna Ehley at Politico: ‘I just started flowing. It was the only thing that helped.’In tough neighborhoods, can high-school mental health counselors cut the school-to-prison pipeline?

Yamiche Alcindor in the New York Times: In Sweltering South, Climate Change Is Now a Workplace Hazard



from ScienceBlogs http://ift.tt/2vZK2ho

A few of the recent pieces I recommend reading:

Larissa MacFarquhar in the New Yorker: When Should a Child Be Taken from His Parents?

Brian Rinker at STAT: 32 churches and no methadone clinic: struggling with addiction in an opioid ‘treatment desert’

Renee Bracey Sherman in the New York Times: The Right to (Black) Life

Brianna Ehley at Politico: ‘I just started flowing. It was the only thing that helped.’In tough neighborhoods, can high-school mental health counselors cut the school-to-prison pipeline?

Yamiche Alcindor in the New York Times: In Sweltering South, Climate Change Is Now a Workplace Hazard



from ScienceBlogs http://ift.tt/2vZK2ho

Science Books: New And Cheap (not necessarily both) [Greg Laden's Blog]

Let’s start with CheMystery.

This is a fun graphic novel mystery book by C.A. Preece and Josh Reynolds. Two cousins experience an incident that would make a physicist cry, but that works in a chemistry book because they now have the ability to observe and change matter. So this is a superhero book, designed to teach chemistry. The story is great, the science is great, and the pedagogy is well suited for kids and adults that like graphic novels.

Preece is the chem teacher (high school) and Reynolds is the artist.

This is written for grades 7 through 10 (ages 8-12) but some younger kids will do fine with it.

This book is pretty new, but I think it is available.

Here are some books that are currently available cheap on Kindle, for anywhere from free to two bucks, that are either science or otherwise, I suspect, of interest to readers of this blog:

Electric Universe: How Electricity Switched on the Modern World

In Praise of Doubt: How to Have Convictions Without Becoming a Fanatic

You Are Not So Smart: Why You Have Too Many Friends on Facebook, Why Your Memory Is Mostly Fiction, an d 46 Other Ways You’re Deluding Yourself

Bad Girls Throughout History: 100 Remarkable Women Who Changed the World

Adams: An American Dynasty



from ScienceBlogs http://ift.tt/2uGPjul

Let’s start with CheMystery.

This is a fun graphic novel mystery book by C.A. Preece and Josh Reynolds. Two cousins experience an incident that would make a physicist cry, but that works in a chemistry book because they now have the ability to observe and change matter. So this is a superhero book, designed to teach chemistry. The story is great, the science is great, and the pedagogy is well suited for kids and adults that like graphic novels.

Preece is the chem teacher (high school) and Reynolds is the artist.

This is written for grades 7 through 10 (ages 8-12) but some younger kids will do fine with it.

This book is pretty new, but I think it is available.

Here are some books that are currently available cheap on Kindle, for anywhere from free to two bucks, that are either science or otherwise, I suspect, of interest to readers of this blog:

Electric Universe: How Electricity Switched on the Modern World

In Praise of Doubt: How to Have Convictions Without Becoming a Fanatic

You Are Not So Smart: Why You Have Too Many Friends on Facebook, Why Your Memory Is Mostly Fiction, an d 46 Other Ways You’re Deluding Yourself

Bad Girls Throughout History: 100 Remarkable Women Who Changed the World

Adams: An American Dynasty



from ScienceBlogs http://ift.tt/2uGPjul

Australia Solar Thermal Plant: Messed up reporting [Greg Laden's Blog]

Trump, Trainwreck, Fascist. [Greg Laden's Blog]

In a series of strange events, President Donald Trump once again invoked violence against a CNN reporter and, apparently, embraced the idea that he is a fascist.

Following the homicidal terrorist attack on anti-White Supremacist demonstrators, trump saw fit to post the following tweet, memorialized here in a retweet by Kyle Griffin, an MSNBC producer.

Similar to an earlier contrived production in which Trump himself is shown in a video beating a CNN reporter, this shows a train labeled TRUMP running over a CNN reporter in cartoon form.

That tweet was deleted soon after being posted. I wonder how that happened. Did Trump think better of his choice? Did General Kelly storm the bathroom and wrestle Trump’s phone away from him? Did the NSA dive in there and delete the offending tweet in such a way that Trump will never see that it was deleted but the rest of us will? Can they even do that?

Meanwhile, a guy from the UK named Mike Holden, tweeted the observation that Trump is a fascist, so his alleged ikntent to pardon Arizona Joe Arpaio, Sheriff makes sense. Astonishingly, trump re-tweeted Holden’s remark.

I checked. Trump’s twitter account does not say “retweets are not endorsement,” and we know from the evidence of considerable prior practice that Trump’s retweets are, in deed, endorsements.

That tweet was also removed, and again, one wonders how that happened.

SNL, are you paying attention?

I found out about these tweets in this WaPo article.. So, it is probably fake, but whatever.



from ScienceBlogs http://ift.tt/2wbjysZ

In a series of strange events, President Donald Trump once again invoked violence against a CNN reporter and, apparently, embraced the idea that he is a fascist.

Following the homicidal terrorist attack on anti-White Supremacist demonstrators, trump saw fit to post the following tweet, memorialized here in a retweet by Kyle Griffin, an MSNBC producer.

Similar to an earlier contrived production in which Trump himself is shown in a video beating a CNN reporter, this shows a train labeled TRUMP running over a CNN reporter in cartoon form.

That tweet was deleted soon after being posted. I wonder how that happened. Did Trump think better of his choice? Did General Kelly storm the bathroom and wrestle Trump’s phone away from him? Did the NSA dive in there and delete the offending tweet in such a way that Trump will never see that it was deleted but the rest of us will? Can they even do that?

Meanwhile, a guy from the UK named Mike Holden, tweeted the observation that Trump is a fascist, so his alleged ikntent to pardon Arizona Joe Arpaio, Sheriff makes sense. Astonishingly, trump re-tweeted Holden’s remark.

I checked. Trump’s twitter account does not say “retweets are not endorsement,” and we know from the evidence of considerable prior practice that Trump’s retweets are, in deed, endorsements.

That tweet was also removed, and again, one wonders how that happened.

SNL, are you paying attention?

I found out about these tweets in this WaPo article.. So, it is probably fake, but whatever.



from ScienceBlogs http://ift.tt/2wbjysZ

Will Scientists Ever Discover Life Without A Home Planet? (Synopsis) [Starts With A Bang]

“An extrapolation of the genetic complexity of organisms to earlier times suggests that life began before the Earth was formed. Life may have started from systems with single heritable elements that are functionally equivalent to a nucleotide.” -Alexei A. Sharov & Richard Gordon

We talk about the origin of life on Earth with bated breath, wondering all the time how things occurred to make our planet unique. But within that big question lies an assumption that may not be true: that life on Earth originated on Earth itself. It’s entirely possible, based on what we’ve seen out there in the Universe, that life didn’t originate here at all. Rather, it could have come from a primitive, pre-existing world, or even from the depths of interstellar space itself.

A rich nebula of gas, pushed out into the interstellar medium by the hot, new stars formed in the central region. Earth may have formed in a region like this, and this region may already be teeming with primitive forms of life, under some set of rules and definitions. Image credit: Gemini Observatory / AURA.

If it’s the latter case — interstellar space — then perhaps we don’t even require a planet at all to create the more primitive forms of life itself. Perhaps all you need is a molecule that encodes information, reproduces itself, and converts external energy for use in biological processes. And if that’s the case, the origin of life may bear very little resemblance to what life has evolved into today.

On this semilog plot, the complexity of organisms, as measured by the length of functional non-redundant DNA per genome counted by nucleotide base pairs (bp), increases linearly with time. Time is counted backwards in billions of years before the present (time 0). Image credit: Shirov & Gordon (2013), via http://ift.tt/2uKyfQg.

Could pretty much all places in the Universe, by the present time, have these ingredients that qualify as life? Let’s look at the evidence!



from ScienceBlogs http://ift.tt/2uFzap9

“An extrapolation of the genetic complexity of organisms to earlier times suggests that life began before the Earth was formed. Life may have started from systems with single heritable elements that are functionally equivalent to a nucleotide.” -Alexei A. Sharov & Richard Gordon

We talk about the origin of life on Earth with bated breath, wondering all the time how things occurred to make our planet unique. But within that big question lies an assumption that may not be true: that life on Earth originated on Earth itself. It’s entirely possible, based on what we’ve seen out there in the Universe, that life didn’t originate here at all. Rather, it could have come from a primitive, pre-existing world, or even from the depths of interstellar space itself.

A rich nebula of gas, pushed out into the interstellar medium by the hot, new stars formed in the central region. Earth may have formed in a region like this, and this region may already be teeming with primitive forms of life, under some set of rules and definitions. Image credit: Gemini Observatory / AURA.

If it’s the latter case — interstellar space — then perhaps we don’t even require a planet at all to create the more primitive forms of life itself. Perhaps all you need is a molecule that encodes information, reproduces itself, and converts external energy for use in biological processes. And if that’s the case, the origin of life may bear very little resemblance to what life has evolved into today.

On this semilog plot, the complexity of organisms, as measured by the length of functional non-redundant DNA per genome counted by nucleotide base pairs (bp), increases linearly with time. Time is counted backwards in billions of years before the present (time 0). Image credit: Shirov & Gordon (2013), via http://ift.tt/2uKyfQg.

Could pretty much all places in the Universe, by the present time, have these ingredients that qualify as life? Let’s look at the evidence!



from ScienceBlogs http://ift.tt/2uFzap9

Naturopathy: When fake doctors cosplay real doctors [Respectful Insolence]

Someone yesterday was not very happy with my attitude towards naturopaths, as evidenced in my post yesterday about the death of a young woman named Jade Erick due to intravenous infusion of curcumin by—you guessed it—a naturopath. Amusingly, that someone going by the ‘nym of JR said that he or she didn’t “like the tone of this article and it’s complete disregard for naturopaths.” Well, JR, you’re right. I do have a complete disregard for naturopaths because they are quacks who mix a small amount of good advice about diet and exercise with a whole lot of pure quackery (like homeopathy) and sell it to patients as being somehow “natural.”

Basically, naturopaths are fake doctors, but they crave the acceptance of real physicians. Whether it’s because they really believe that they are physicians or because, deep down, they know they are fake doctors, I don’t know. Maybe it’s a little of both. Either way, above all their professional organizations strive for legitimacy in the form of being licensed by all 50 states. They even have a goal of having naturopaths licensed in all states by 2025. But it’s more than that. In states where they are already licensed, their goal is to expand their scope of practice to come close to that of real physicians.

So I can’t believe that I missed this story that was going around a couple of weeks ago from the Denver CBS affiliate about Naturopathic Doctors Illegally Calling Themselves ‘Physicians’:

I can’t resist mentioning here that I think that letting naturopaths refer to themselves as “doctors” or “naturopathic doctors” is bad enough, because most people don’t make that big a distinction between “doctor” and “physician.” Als, their favored abbreviation for their degree of”ND” looks and sounds and awful lot like a real doctor’s degree of MD. Be that as it may, things are a bit different in Colorado than in a lot of states that license naturopaths. For one thing, there is a law specifically stating that naturopaths cannot refer to themselves as “physicians.” The law came about this way:

The death of Sean Flanagan in 2003 touched off a storm. Ill with cancer, he received treatment from a man who called himself a naturopathic doctor practicing in Wheat Ridge.

Sean’s father David Flanagan told CBS4’S Rick Sallinger three years later about his dismay.

“We’ve got people like Brian O’Connell who can claim to be a doctor and use the word, put it on his scrubs, wear a stethoscope like he’s somebody important,” he said.

Although Flanagan died from cancer, Brian O’Connell’s actions may have sped up his death.

He was sent to prison and legislation was later passed by the state to register naturopathic doctors. In the law one point was made very clear: naturopaths cannot refer to themselves by a key word: “physician.”

I had never heard about this case (at least, I couldn’t remember having heard about it); so I did a little Googling. It turns out that O’Connell ran Mountain Area Naturopathic Associates. Consistent with what David Flanagan said in the interview above, in his office O’Connell displayed numerous degrees and certifications claiming he was doctor and a naturopath. In an investigation, the Colorado Medical Board found that O’Connell had no license to practice medicine in Colorado and was not certified as any kind of health care worker. It also turned out that O’Connell’s only medical-related “training” had come from a correspondence school in Arkansas called the Herbal Healer academy. As Naturowatch notes, in 2003 the school’s proprietor Marijah McCain agreed to a consent judgment under which she paid $10,000 and was barred from disseminating certificates stating that the holder is an “ND, NMD,” or similar designation that would indicate that the holder is a doctor or physician.

Naturowatch also notes:

  • O’Connell told the family that he personally had “cured” many patients suffering from the same type of cancer he had. He also showed them a plastic bag containing an object he claimed was a cancerous tumor removed from a patient and claimed that he had a black salve that would draw cancerous tumors from the body. Flanagan had failed a course of chemotherapy and his cancer was progressing. Also, black salve is not just quackery, but disfiguring quackery. It’s a caustic substance derived from plants that literally burns.
  • The family paid O’Connell $7,400 for “photoluminescence” treatments in which blood was removed from Sean Flanagan’s body, exposed to ultraviolet light, and then returned to the body along with a diluted solution of hydrogen peroxide. Both of these, UV blood irradiation and intravenous hydrogen peroxide, are also quackery. Basically, it’s UV blood irradiation combined with hydrogen peroxide therapy.
  • The boy developed a blood infection because O’Connell’s wasn’t exactly careful about sterile technique.

Also:

O’Connell also injected this hydrogen peroxide solution into a 17-year-old girl, which caused her to go into cardiac arrest. Another patient of O’Connell’s had terminal liver cancer and was told by O’Connell that a “black salve” compound would pull the cancer out of his body. Instead it created open, bleeding wounds that continued until his death, prosecutors said.

In other words, even though he didn’t have the “ND” degree, O’Connell was a typical naturoquack. Ultimately, he was convicted. In 2006, he pleaded guilty to theft, perjury, criminally negligent homicide, practicing medicine without a license, and 3rd degree assault. As a result, he was sentenced to 13 years in prison, which was a salutary outcome which is all too rare when quacks are prosecuted.

As a result of this case, when Colorado passed a law registering—not licensing—naturopaths, the law made it very clear that naturopaths are not allowed to refer to themselves as physicians. Now, I’m not exactly clear on the difference between licensure and registration, but apparently registration provides for a much less rigorous degree of scrutiny of naturopaths than licensure would. Basically, according to Colorado law, naturopaths who have gone to the top tier naturopathy quack academies, like Bastyr University, and as a result have the “ND” degree can call themselves “doctor” but not physician. All other naturopaths are forbidden from calling themselves “doctor” or “physician.” Of course, one wonders why such naturopaths are even allowed to practice, although I suppose that, despite what “NDs” claim, there really isn’t any substantive difference that I’ve ever been able to find in the level of quackery practiced by NDs or non-ND naturopaths. Basically, licensed naturopaths are no safer than any other naturopath.

Be that as it may, even though the law expressly forbids it, naturopaths gonna naturopath:

Larry Sarner and Linda Rosa of the Colorado Citizens for Science and Medicine conducted a survey of websites and claim most naturopathic doctors violate the Colorado Medical Practices Act and State Statutes.

Sarner said, “It would be almost hard not to believe they are medical doctors given their own discussions of it.”

Some naturopathic doctors claim they are licensed. They can’t be. The state of Colorado says they are simply registered, which carries less scrutiny.

Not surprisingly, Roanne Houck, the president of the Colorado Association of Naturopathic Doctors, makes excuses:

“Well, many of the doctors have moved here from other states such as Oregon or Washington,” she said.

They may be called physicians there, but in Colorado, for naturopaths that’s not allowed.

Naturopathic doctors may now also go by “Registered Naturopathic Doctors” in Colorado after new legislation was passed earlier this year.

That’s nice. It’s still confusing and potentially deceptive, leading patients to think that naturopaths are actually physicians.

Just for yucks, I looked up Houck’s practice website, Gunnison Main Street Clinic. I noticed that it offers the usual naturopathic quackery, such as The One Quackery To Rule Them All (homeopathy), “detoxification,” acupuncture and traditional Chinese medicine, and something called Ortho-Bionomy®, which is basically a form of osteopathic manipulation that I’d never heard of before.

Of course, at least Colorado doesn’t let naturopaths use the term “physician” to describe themselves. Lots of other states, where naturopaths are licensed and not just registered, do let naturopaths use terms like “naturopathic physician,” the favored term of organized naturopathy. Naturopaths continue to push for this, because they know that language feeds impressions. If they can win the legal right to be called “naturopathic physicians,” chances are that a lot of people won’t know the difference between that and real physicians and that legislators will be more likely to expand their scope of practice to reach their Holy Grail, being considered primary care physicians in all 50 states.



from ScienceBlogs http://ift.tt/2fHnQ58

Someone yesterday was not very happy with my attitude towards naturopaths, as evidenced in my post yesterday about the death of a young woman named Jade Erick due to intravenous infusion of curcumin by—you guessed it—a naturopath. Amusingly, that someone going by the ‘nym of JR said that he or she didn’t “like the tone of this article and it’s complete disregard for naturopaths.” Well, JR, you’re right. I do have a complete disregard for naturopaths because they are quacks who mix a small amount of good advice about diet and exercise with a whole lot of pure quackery (like homeopathy) and sell it to patients as being somehow “natural.”

Basically, naturopaths are fake doctors, but they crave the acceptance of real physicians. Whether it’s because they really believe that they are physicians or because, deep down, they know they are fake doctors, I don’t know. Maybe it’s a little of both. Either way, above all their professional organizations strive for legitimacy in the form of being licensed by all 50 states. They even have a goal of having naturopaths licensed in all states by 2025. But it’s more than that. In states where they are already licensed, their goal is to expand their scope of practice to come close to that of real physicians.

So I can’t believe that I missed this story that was going around a couple of weeks ago from the Denver CBS affiliate about Naturopathic Doctors Illegally Calling Themselves ‘Physicians’:

I can’t resist mentioning here that I think that letting naturopaths refer to themselves as “doctors” or “naturopathic doctors” is bad enough, because most people don’t make that big a distinction between “doctor” and “physician.” Als, their favored abbreviation for their degree of”ND” looks and sounds and awful lot like a real doctor’s degree of MD. Be that as it may, things are a bit different in Colorado than in a lot of states that license naturopaths. For one thing, there is a law specifically stating that naturopaths cannot refer to themselves as “physicians.” The law came about this way:

The death of Sean Flanagan in 2003 touched off a storm. Ill with cancer, he received treatment from a man who called himself a naturopathic doctor practicing in Wheat Ridge.

Sean’s father David Flanagan told CBS4’S Rick Sallinger three years later about his dismay.

“We’ve got people like Brian O’Connell who can claim to be a doctor and use the word, put it on his scrubs, wear a stethoscope like he’s somebody important,” he said.

Although Flanagan died from cancer, Brian O’Connell’s actions may have sped up his death.

He was sent to prison and legislation was later passed by the state to register naturopathic doctors. In the law one point was made very clear: naturopaths cannot refer to themselves by a key word: “physician.”

I had never heard about this case (at least, I couldn’t remember having heard about it); so I did a little Googling. It turns out that O’Connell ran Mountain Area Naturopathic Associates. Consistent with what David Flanagan said in the interview above, in his office O’Connell displayed numerous degrees and certifications claiming he was doctor and a naturopath. In an investigation, the Colorado Medical Board found that O’Connell had no license to practice medicine in Colorado and was not certified as any kind of health care worker. It also turned out that O’Connell’s only medical-related “training” had come from a correspondence school in Arkansas called the Herbal Healer academy. As Naturowatch notes, in 2003 the school’s proprietor Marijah McCain agreed to a consent judgment under which she paid $10,000 and was barred from disseminating certificates stating that the holder is an “ND, NMD,” or similar designation that would indicate that the holder is a doctor or physician.

Naturowatch also notes:

  • O’Connell told the family that he personally had “cured” many patients suffering from the same type of cancer he had. He also showed them a plastic bag containing an object he claimed was a cancerous tumor removed from a patient and claimed that he had a black salve that would draw cancerous tumors from the body. Flanagan had failed a course of chemotherapy and his cancer was progressing. Also, black salve is not just quackery, but disfiguring quackery. It’s a caustic substance derived from plants that literally burns.
  • The family paid O’Connell $7,400 for “photoluminescence” treatments in which blood was removed from Sean Flanagan’s body, exposed to ultraviolet light, and then returned to the body along with a diluted solution of hydrogen peroxide. Both of these, UV blood irradiation and intravenous hydrogen peroxide, are also quackery. Basically, it’s UV blood irradiation combined with hydrogen peroxide therapy.
  • The boy developed a blood infection because O’Connell’s wasn’t exactly careful about sterile technique.

Also:

O’Connell also injected this hydrogen peroxide solution into a 17-year-old girl, which caused her to go into cardiac arrest. Another patient of O’Connell’s had terminal liver cancer and was told by O’Connell that a “black salve” compound would pull the cancer out of his body. Instead it created open, bleeding wounds that continued until his death, prosecutors said.

In other words, even though he didn’t have the “ND” degree, O’Connell was a typical naturoquack. Ultimately, he was convicted. In 2006, he pleaded guilty to theft, perjury, criminally negligent homicide, practicing medicine without a license, and 3rd degree assault. As a result, he was sentenced to 13 years in prison, which was a salutary outcome which is all too rare when quacks are prosecuted.

As a result of this case, when Colorado passed a law registering—not licensing—naturopaths, the law made it very clear that naturopaths are not allowed to refer to themselves as physicians. Now, I’m not exactly clear on the difference between licensure and registration, but apparently registration provides for a much less rigorous degree of scrutiny of naturopaths than licensure would. Basically, according to Colorado law, naturopaths who have gone to the top tier naturopathy quack academies, like Bastyr University, and as a result have the “ND” degree can call themselves “doctor” but not physician. All other naturopaths are forbidden from calling themselves “doctor” or “physician.” Of course, one wonders why such naturopaths are even allowed to practice, although I suppose that, despite what “NDs” claim, there really isn’t any substantive difference that I’ve ever been able to find in the level of quackery practiced by NDs or non-ND naturopaths. Basically, licensed naturopaths are no safer than any other naturopath.

Be that as it may, even though the law expressly forbids it, naturopaths gonna naturopath:

Larry Sarner and Linda Rosa of the Colorado Citizens for Science and Medicine conducted a survey of websites and claim most naturopathic doctors violate the Colorado Medical Practices Act and State Statutes.

Sarner said, “It would be almost hard not to believe they are medical doctors given their own discussions of it.”

Some naturopathic doctors claim they are licensed. They can’t be. The state of Colorado says they are simply registered, which carries less scrutiny.

Not surprisingly, Roanne Houck, the president of the Colorado Association of Naturopathic Doctors, makes excuses:

“Well, many of the doctors have moved here from other states such as Oregon or Washington,” she said.

They may be called physicians there, but in Colorado, for naturopaths that’s not allowed.

Naturopathic doctors may now also go by “Registered Naturopathic Doctors” in Colorado after new legislation was passed earlier this year.

That’s nice. It’s still confusing and potentially deceptive, leading patients to think that naturopaths are actually physicians.

Just for yucks, I looked up Houck’s practice website, Gunnison Main Street Clinic. I noticed that it offers the usual naturopathic quackery, such as The One Quackery To Rule Them All (homeopathy), “detoxification,” acupuncture and traditional Chinese medicine, and something called Ortho-Bionomy®, which is basically a form of osteopathic manipulation that I’d never heard of before.

Of course, at least Colorado doesn’t let naturopaths use the term “physician” to describe themselves. Lots of other states, where naturopaths are licensed and not just registered, do let naturopaths use terms like “naturopathic physician,” the favored term of organized naturopathy. Naturopaths continue to push for this, because they know that language feeds impressions. If they can win the legal right to be called “naturopathic physicians,” chances are that a lot of people won’t know the difference between that and real physicians and that legislators will be more likely to expand their scope of practice to reach their Holy Grail, being considered primary care physicians in all 50 states.



from ScienceBlogs http://ift.tt/2fHnQ58

Mary’s Monday Metazoan: Son of Spongebob [Pharyngula]

The sequel is going to go a bit dark: this is a deep ocean sponge. It’s dark and ominous, and it’s also carnivorous, with sticky spines for capturing and killing passing animals.

I think that thing has been waiting for me in a lot of my nightmares.



from ScienceBlogs http://ift.tt/2uIwbIw

The sequel is going to go a bit dark: this is a deep ocean sponge. It’s dark and ominous, and it’s also carnivorous, with sticky spines for capturing and killing passing animals.

I think that thing has been waiting for me in a lot of my nightmares.



from ScienceBlogs http://ift.tt/2uIwbIw

Five Things You Must Not Do During Totality At The Solar Eclipse (Synopsis) [Starts With A Bang]

“Yes, I am well aware that nature — or what we call nature: that totality of objects and processes that surrounds us and that alternately creates us and devours us — is neither our accomplice nor our confidant.” -Octavio Paz

For most of us heading to the path of totality, we’re in for an incredible experience. If we get clear skies, it will take roughly an hour for the Moon to pass in front of the Sun’s disk completely, and after that we’ll get just over two minutes of totality: an experience like no other. Yet if you’re not careful — or if you get too excited about one particular thing — you might miss the best parts.

Messing around with photography is a great way to miss the incredible sights, sounds, and experiences of a total solar eclipse. Unless you’ve experienced enough total eclipses that you don’t mind missing one, leave photography to the pros. Image credit: Beawiharta/Reuters.

A lot of photography enthusiasts are planning to capture the eclipse on film (or digitally), but that may be a very poor decision. Others are planning on using binoculars to get a better view of the corona, but that has extreme dangers. Others aren’t sure whether they need their eclipse glasses or what all the things they should look for and try to experience are. But there are too many scientists passionate about getting the right information out there to let this event go by without sharing that knowledge and wonder with the world.

A panorama of the 2012 solar eclipse shows a region of darkness in the night sky, surrounded by the bright region where the Moon’s eclipse shadow does not land. Image credit: Jan Sladecek; Miloslav Druckmuller.

There will be an awful lot to take in during those moments of total darkness, and there’s no substitute for knowing what to expect. Here are five pitfalls you must avoid.



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“Yes, I am well aware that nature — or what we call nature: that totality of objects and processes that surrounds us and that alternately creates us and devours us — is neither our accomplice nor our confidant.” -Octavio Paz

For most of us heading to the path of totality, we’re in for an incredible experience. If we get clear skies, it will take roughly an hour for the Moon to pass in front of the Sun’s disk completely, and after that we’ll get just over two minutes of totality: an experience like no other. Yet if you’re not careful — or if you get too excited about one particular thing — you might miss the best parts.

Messing around with photography is a great way to miss the incredible sights, sounds, and experiences of a total solar eclipse. Unless you’ve experienced enough total eclipses that you don’t mind missing one, leave photography to the pros. Image credit: Beawiharta/Reuters.

A lot of photography enthusiasts are planning to capture the eclipse on film (or digitally), but that may be a very poor decision. Others are planning on using binoculars to get a better view of the corona, but that has extreme dangers. Others aren’t sure whether they need their eclipse glasses or what all the things they should look for and try to experience are. But there are too many scientists passionate about getting the right information out there to let this event go by without sharing that knowledge and wonder with the world.

A panorama of the 2012 solar eclipse shows a region of darkness in the night sky, surrounded by the bright region where the Moon’s eclipse shadow does not land. Image credit: Jan Sladecek; Miloslav Druckmuller.

There will be an awful lot to take in during those moments of total darkness, and there’s no substitute for knowing what to expect. Here are five pitfalls you must avoid.



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The death of Jade Erick from intravenous curcumin: Mystery solved [Respectful Insolence]

Kim Kelly, ND (Not A Doctor). He prescribed the dose of intravenous turmeric that killed Jade Erick.

Finally, a mystery has been solved.

Nearly five months ago, a 30 year old woman named Jade Erick suffered a cardiac arrest, most likely due to anaphylactic shock, during the infusion of intravenous curcumin ordered by a California naturopath named Kim Kelly, ND (for Not-a-Doctor). Because Erick’s death was so sudden and dramatic, the story briefly made national news. I viewed the tragic incident as yet another example of why “licensed” naturopaths, such as those in California or other states that have made the mistake of passing laws allowing the licensing of naturopaths, are no less likely to mess up your health or even kill you than “unlicensed” naturopaths, such as the naturopath in Bowling Green who was shot by the husband of one of his patients. The reason for the shooting? That naturopath had told the man’s wife that “chemo is for losers” and treated her with the usual naturopathic voodoo, allowing the woman’s cancer to progress until it was no longer treatable with conventional medicine.

Jade Erick didn’t suffer from a life-threatening disease like cancer. She did, however, have a condition that almost certainly significantly affected her quality of life for the worse, namely eczema. Eczema is the name commonly given a group of medical conditions characterized by inflammation of the skin (i.e., rashes). The most common type of eczema is known as atopic dermatitis or atopic eczema, with the “atopic” referring to a group of diseases with an often inherited tendency to develop other allergic conditions. It’s a pretty common condition, too, with around 10% to 20% of infants being affected and around 3% of adults. Most children with eczema “outgrow” it, but some people continue to have symptoms on and off for the rest of their lives. Because eczema’s clinical course can be so varied and intermittent and also because the itching it causes can be very intense, it is a magnet for quacks like naturopaths. There are, of course, conventional medical treatments for eczema that relieve the itching and irritation and prevent rashes, but they leave much to be desired, again another characteristic of diseases or conditions that are quack magnets.

A little over a week ago, a number of readers sent me a link to an FDA safety alert and report of its investigation into Erick’s death and another case of a serious hypersensitivity reaction due to intravenous curcumin. Included with these two links was a link to an alert about the risk of compounding medications. It turns out that what likely killed Jade Erick was a hypersensitivity reaction to the use of a component that wasn’t pharmaceutical grade and is also known to cause hypersensitivity reactions. Let’s take a look.

Jade Erick and the naturopath who killed her

As I mentioned before, Jade Erick was an otherwise healthy 30 year old woman with a chronic medical condition. For whatever reason, however she found him, she sought out treatment from a naturopath named Kim Kelly, who, as it turns out, has been a vocal advocate of intravenous curcumin to treat…just about everything. Indeed, although after Erick’s death Kelly started scrubbing every mention of intravenous curcumin from his website, enough remained to demonstrate his enthusiasm for its use:

I am excited to announce that I’ve started administering intravenous curcumin. Curcumin has been used for thousands of years for culinary and medicinal reasons. People have used it to help with pain, inflammation, immune system, arthritis, liver conditions and cancer. It’s also been found that intravenous curcumin in combination with vitamin C and glutathione (I call it the “Mother of All Antioxidants”) has a potentiating effecting in helping people with chronic health conditions e.g. hepatitis C, liver fibrosis. Intravenous Curcumin is absorbed better, faster and can be given in much higher doses compared to taking it orally. Therefore, the benefits usually can be seen much sooner. Patients who have received it thus far have reported benefits very soon after treatment.

If you are suffering from any type of inflammatory condition, whether it be arthritis, autoimmune condition (e.g. scleroderma, lupus or rheumatoid arthritis), Alzheimers or dementia, this may be a great modality of treatment to try. It may require multiple treatments or may be just one treatment, depending on each person and the condition.

The safety, tolerability, and nontoxicity of curcumin at high doses have been well established by human clinical trials. Promising effects have been observed in patients with various pro-inflammatory diseases.

I can’t help but note that that last statement is absolutely false. Yes, orally administered curcumin is generally pretty safe even up to 8 g per day. However, intravenous curcumin hasn’t been well studied, as I discovered when I started doing more PubMed searches (although I did find a bunch of articles in which investigators were trying to use curcumin nanoparticles, micelles, and the like to administer curcumin IV). This is naturopathic “reasoning,” such as it is: If a little is good, a boatload would be better. Finally, if real medical science is investigating a natural product for one indication and it shows a bit of promise, then to naturopaths it must be a wonder medicine that cures everything—and I do mean everything. Take a look at the list of conditions for which Kelly claims treatment efficacy of IV curcumin:

INFLAMMATORY DISEASES

  • Inflammatory Bowel Disease (Crohn’s and Ulcerative Colitis)
  • Osteoarthritis
  • Post-Operative Inflammation
  • Irritable Bowel Syndrome
  • H. pylori infection

METABOLIC DISEASES:

  • Type 2 Diabetes
  • Diabetic Nephropathy

SKIN:

  • Psoriasis
  • Vitiligo

OTHERS:

  • Beta-Thalassemia
  • Hepatoprotection
  • Alcohol Intoxication
  • Chronic bacterial prostatitis
  • Alzheimer’s
  • Atherosclerosis
  • Arsenic Exposure

Oddly enough, eczema is not on the list. Obviously, “Dr.” Kelly expanded his list before treating Ms. Erick. In any case, it’s always a huge red flag when I see a long list of unrelated diseases and conditions treated by the same drug or treatment. I mean, chronic bacterial prostatitis and atherosclerosis and arsenic exposure? Seriously? In any event, although curcumin has been a favorite of naturopaths for a long time, intravenous curcumin is a relative newcomer on the quack scene. The foremost promoter and popularizer of infusing this compound directly into the veins instead of administering it orally is Paul Anderson, who, as we will see, was so concerned about this death that he issued a disingenuous defense of what Kelly did.

As for Kelly himself, as I like to say, he is everything that organized naturopathy says a good “naturopathic physician” should be. Just look at his profile on his website:

Dr. Kim D. Kelly graduated from Bastyr University in 2001 and is a licensed Naturopathic doctor in the state of California. Growing up on a farm in Northern Minnesota is where he first had experience in the healing power of nature. This was further fostered when reading about the numerous clinical trials using alternative therapies when he was getting his Master’s of Public Health (MPH in Epidemiology) at the University of Minnesota. After realizing the power and effectiveness of alternative therapies, his career goal as Epidemiologist changed to wanting to become a Naturopathic Doctor; thus, he enrolled at Bastyr University in Seattle, WA.

Upon graduation from Bastyr, he underwent a rigorous three year training program at a cutting edge clinic, where he was trained by a team of medical and naturopathic doctors (Nazanin Kimiai, ND, LAc; Dietrich Klinghardt, MD, PhD; David Musnick, MD, MPH). Through his experience at this integrative clinic, Dr. Kelly learned the art and science of progressive healing modalities for musculoskeletal pain, autoimmune conditions, chronic infections (parasites, Lyme, mold), environmental & heavy metal toxicities and general health issues.

Dr. Kelly’s four years as technical director and consultant with Sabre Sciences has given him a strong background on use of bio-identical hormones and neurotransmitters for issues e.g. menopausal and andropause symptoms, PMS, insomnia, anxiety or chronic fatigue. His specialties include adrenal fatigue, thyroid disorders, hormonal issues in men and women (menopause, andropause, PMS, etc.), musculoskeletal pain and heavy metal detoxification. A lot of his practice also involves a technique called Biopuncture to help with chronic pain, headaches, gastritis, IBS and other health issues (See Service List for more details). He currently has an office in Encinitas.

Dr. Kelly has lectured locally and nationally on topics e.g. hormone balance for men and women, heavy metal toxicity and what we can do, nutritional research on Autism, gastrointestinal issues and natural medicine in San Diego.

In the world of naturopathy, Bastyr is the equivalent of Harvard or Stanford. Of course, being the Harvard or Stanford of quack schools is not saying much. After all, Bastyr recently sent a cease-and-desist letter to Britt Hermes, a former naturopath who graduated from Bastyr but eventually came to the realization that naturopathy is pure quackery and has been unrelentingly critical of her former alma mater ever since. My point, of course, is that Kelly graduated from what groups like the American Association of Naturopathic Physicians (AANP) view as the crème de la crème of naturopathy schools and is fully licensed in the largest state in the country. Of course, I can’t help but note that in his bio asserting his pseudoprofessional bona fides, he can’t help but mention one of naturopaths’ favorite forms of quackery, “heavy metal detox.” I find that appropriate.

Perusing the rest of Kelly’s website, even without the benefit of the almighty Wayback Machine at Archive.org, which rescues web pages from the memory hole every day, I found plenty of quackery offered by his practice. For instance, he offers biopuncture, naturopathic detoxing, hormonal balance treatment, IV nutrition, and “wellness programs.” Biopuncture, I note, is an unholy combination of acupuncture and homeopathy so quacky that Dr. Oz promoted it. Kelly describes it thusly:

Biopuncture is a technique that combines neural therapy, trigger point therapy, prolotherapy and homotoxicology. It stimulates the body’s own healing mechanisms thus speeding up the process of injury recovery, natural rejuvenation/repair and also lowers pain and inflammation. The technique involves using pin-prick needles to inject miniature amounts of homeopathic remedies under the skin or into muscle encouraging the body to start healing and to help stimulate local blood circulation.

In other words, it’s some most excellently ridiculous woo, a witches’ brew of quackery, to go along with all the other nonsense in Kelly’s blog, such as (of course) more biopuncture and more “detoxification,” along with other quackery such as adrenal fatigue treatment, intravenous vitamin C, and a dangerous modality like intravenous peroxide for chronic infections. All of this costs only $150 per 30 minutes plus the cost of the therapy.

Not surprisingly, when a real medical emergency happened right in his own office, “Dr.” Kelly wasn’t prepared to deal with it. The result is described in the FDA report:

On March 10, 2017, the U.S. Food and Drug Administration received an adverse event report concerning a 30-year-old female patient who experienced cardiac arrest after IV administration of a curcumin emulsion product compounded by ImprimisRx. The patient reportedly had a history of allergies and was being treated for eczema by a naturopathic doctor. Within minutes of starting the infusion, the patient became pulseless and required CPR. The patient suffered anoxic (depleted oxygen) brain injury and subsequently died. An adverse reaction to infused curcumin solution was identified as a cause of death by the local authorities.

So what caused the hypersensitivity reaction that killed Jade Erick within minutes of the start of her infusion of IV curcumin? The FDA thinks it’s found the cause both of her death and of a similar hypersensitivity that nearly killed a 71 year old man who was being treated for thrombocytopenia (a low platelet count) at a holistic health center. Amazingly, that “holistic” health center appears to have actually had medications to deal with an acute anaphylactic reaction, which kept him alive long enough to get him to an emergency room. In fairness, Erick’s reaction appears to have been so fast that there might not have been time to administer diphenhydramine and epinephrine.

Beware compounding pharmacies that play fast and loose with ingredients

In response to the reports of Jade Erick’s sudden death, the FDA did what the FDA does very well. It investigated. It turns out that the intravenous curcumin emulsion used was manufactured by ImprimisRx Pharmaceuticals, a compounding pharmacy based in San Diego, California. There are, of course, legitimate compounding pharmacies, and such pharmacies serve a useful role in medicine, but there are also a lot of compounding pharmacies that cater to naturopaths, mixing up combinations of supplements, “natural” medications, and the like for that particular market. ImprimisRx appears to be one such pharmacy, manufacturing both legitimate FDA-approved drugs and compounds like its Curcumin Emulsion MDV and, of course, intravenous vitamin C. It also manufactures intravenous EDTA for chelation therapy.

The FDA collected samples from the IV bag used to dose Jade Erick and from the ImprimisRx curcumin emulsion vial used to prepare the IV bag. It also analyzed the samples of ImprimisRx’s curcumin emulsion product and identified the presence of certain contaminants and impurities. It found a number of rather interesting (and disturbing) things. First, the FDA noted that there wasn’t nearly as much curcumin in ImprimisRx’s curcumin emulsion product as claimed on the labeling. The solution in the IV bag contained only 2.34 μg/mL of curcuminoids, which is only around 1% of the curcumin concentration intended to be administered. It also found that the concentration in the emulsion vial contained only around 0.205 mg/mL of curcuminoids, which is less than 2% of the curcumin concentration represented on the label. One of the big problems with administering curcumin is that it undergoes rapid degradation at physiologic pH, and that might explain why the concentration of curcumin in the vial was so much lower than what was represented on the label. Of course, a good compounding pharmacy should know these issues and limitations and take steps to mitigate them. Clearly ImprimisRx did not. As a result, Kelly and all the naturopaths who thought they were giving their patients “high dose” curcumin were probably giving them less than what a patient would get by taking curcumin supplements orally.

More importantly and relevant to what caused Jade Erick’s death, the FDA found this:

FDA collected and analyzed samples of PEG 40 castor oil from the same lot of ImprimisRx curcumin emulsion product that was administered to the female patient. FDA identified 1.25% w/w DEG [diethylene glycol] in the PEG [polyethylene glycol] 40 castor oil. The label of the tested PEG 40 castor oil includes the warning “CAUTION: For manufacturing or laboratory use only.” The PEG 40 castor oil used by ImprimisRx was ungraded, and not, for example, pharmaceutical grade or food grade. Ungraded products are suitable for general industrial or research purposes and typically are not suitable for human consumption or therapeutic use. There is no U.S. Pharmacopeia (USP) monograph for PEG 40 castor oil.

The FDA notes that drugs, including FDA-approved products, containing polyethylene glycol castor oil have been “associated with severe and sometimes fatal hypersensitivity reactions and include warnings about these reactions in their labels.” One example IV paclitaxel containing Cremophor® EL (PEG 35 castor oil), which can cause severe hypersensitivity reactions in up to 20% of patients. That’s why patients receiving paclitaxel are premedicated with steroids, and it’s why a new formulation lacking the PEG 35 castor oil, Abraxane, is coming into wider usage. The FDA further noted:

Some of the other ingredients in ImprimisRx’s product, including curcumin, also have been associated with hypersensitivity reactions when administered intravenously. There are reports of contact allergies to a metabolite of curcumin, tetrahydrocurcumin, for instance. In addition, there is little to no toxicologic or clinical information available regarding the safety of IV curcumin, and evidence is lacking that curcumin is an effective therapy for eczema or thrombocytopenia. There are no FDA-approved curcumin for injection products.

The ungraded PEG 40 castor oil in ImprimisRx’s curcumin emulsion product may have contained components that resulted in the hypersensitivity reactions. Castor bean seeds and pollens are known to be associated with hypersensitivity reactions. Food grade castor oil is processed to remove the potentially allergenic castor bean constituents, but ungraded PEG 40 castor oil may not be allergen free. In addition to allergens, other potentially harmful contaminants and impurities could be present in the ungraded PEG 40 castor oil.

It was also noted that DEG is a central nervous system depressant, as well as a potent kidney and liver toxin that can cause kidney failure. It’s commonly used in industrial products like antifreeze and brake fluid.

The FDA concluded:

FDA’s investigation into the adverse events associated with ImprimisRx’s curcumin emulsion product for injection highlights some of the risks associated with compounded drugs, particularly those that use non-pharmaceutical grade components and ingredients lacking a USP monograph. The risks illustrated in this case include:

  • the absence of a label warning about hypersensitivity reactions associated with the PEG 40 castor oil;
  • the use of an ungraded inactive ingredient, i.e., PEG 40 castor oil, that is not suitable for human consumption or therapeutic use and may contain impurities such as DEG; and
  • the IV administration of curcumin, despite the fact that its safety profile by this route of administration has not been established, nor has its effectiveness in treating eczema or thrombocytopenia.

So basically, it appears from the FDA report that a perfect storm of woo killed Jade Erick: A naturopath using an unproven treatment plus a compounding pharmacy cutting corners manufacturing its products using PEG 40 castor oil that wasn’t pharmaceutical grade and failing to place a warning label on its curcumin emulsion warning that components of the emulsion can cause hypersensitivity reactions. According to the FDA, ImprimisRx recalled its unexpired products containing the ungraded castor oil on June 23, 2017, which was over two months after the second hypersensitivity reaction (in the 71 year old man) was reported.

The danger of some compounding pharmacies

Another lapse in this case included that there was no prescription for the IV curcumin found. At least, the company told a media outlet that it did not have a prescription. Britt Hermes, in her discussion of the case, speculated based on her experience as a naturopath about how such a thing might have happened and how Kelly might have obtained the curcumin for Erick without a prescription:

Kelly may have used a vial of the curcumin emulsion that was obtained under a prescription for another one of his patients. My former naturopathic colleagues in Arizona at times purchased compounded products in bulk for a single patient to then be used for multiple patients. This stockpiling allowed naturopathic doctors to have compounded drugs on-hand, thereby expediting treatments for multiple patients using only one prescription. Or, Kelly may have obtained the curcumin emulsion from a physician or another naturopathic doctor who had product on hand for their own patients. The borrowing of medical supplies, including compounded substances, is a common practice in the naturopathic community. Either way, using a prescription of one patient for another patient is not permitted by the FDA.

Worse, this sort of occurrence can’t be said to have been entirely unexpected, given ImprimisRx’s previous run-in with the FDA. Last year, the FDA inspected ImprimisRx’s manufacturing facility in Pennsylvania and found a number of violations. These included failures to test:

  • aqueous solutions and suspensions or encapsulated powders to determine if they meet specifications for the intended, labeled dose of active drug ingredient
  • products intended for inhalation to verify that the particle size is correct
  • inhalation products for microbial contamination
  • products to determine appropriate expiration dates

The inspection also found that there were “no written procedures for production and process controls to assure that the drug products have the identity, strength, quality, and purity they purport or are represented to possess,” which likely explains a lot about how the curcumin emulsion could have a potency of only 2% of what was claimed on the label, especially since the FDA found a number of other lapses indicating what can only be called a lack of concern for preventing bacterial contamination and assuring that what is in the product matches what the label says.

Compounding pharmacies can play an important role in medicine. For instance, special compounding might be required if a patient needs a medication to be made without a certain dye or inactive ingredient because of an allergy or needs a medication in liquid or suppository form that is not manufactured in such forms. Unfortunately, a lot of companies go beyond such needs, as the FDA noted in a recent article on compounding pharmacies:

“Some aspects of these firms’ operations appear more consistent with those of drug manufacturers than with those of traditional pharmacies,” says Bernstein. “Some firms make large amounts of drugs that appear to be copies of FDA-approved, commercially available drugs when it does not appear that there is a medical need for an individual patient to receive a compounded version of the drug.”

The FDA also expressed concerns about compounding pharmacies just this year, noting serious incidents linked with them. Most of these incidents have to do with contamination with microorganisms. For instance, in 2012, there was an outbreak of fungal meningitis linked to an injectable steroid medication manufactured by a compounding pharmacy. In 2011 and 2012, 33 eye surgery patients in seven states suffered a rare fungal infection of the eye linked to injectable drug products, resulting in partial to severe vision loss, while in 2011 repackaged injections of Avastin (bevacizumab) also caused serious eye infections in the Miami area. These latter two incidents resulted in serious vision loss in some patients. Some patients injected with the contaminated Avastin lost the remaining vision in the eye being treated.

It’s stories like this that make me laugh derisively any time I hear a politician complain about FDA “overreach.” In reality, the reason these sorts of incidents occur with a distressing regularity is because the FDA is underfunded and understaffed. It has a hard time overseeing pharmaceutical company manufacturing facilities adequately, much less compounding pharmacies, allowing compounding pharmacies like ImprimisRx to continue doing business. Indeed, look at Imprimis Pharmaceuticals’ (IMMY) statement regarding the FDA’s findings. Basically, the company is trying to shift the blame for Jade Erick’s death from its product to…well…anyone else.

For example:

Imprimis had no knowledge of the allergy histories of the subject patients.

So what? Imprimis manufactured a product with components known to cause acute hypersensitivity reactions, and there was no warning of this on the product label.

FDA testing of the IV bag from the 30 year-old patient revealed “no drugs or poisons including diethylene glycol [DEG] at a level greater than 0.1% by volume, were identified in the IV bag contents using GC-MS.” We believe that evidence thus far does not support the 30 year-old patient’s death being caused by PEG 40 Castor Oil or DEG.

WTF? 0.1% is a high concentration for “drugs or poisons.” Basically, it’s one part in a thousand. This is not something that strikes me as exonerating Imprimis. Quite the contrary. It suggests that the FDA was quite correct about Imprimis’ shoddy manufacturing if “drugs or poisons” other than what was supposed to be in the product were present at a concentration as high as 0.1% Again, WTF?

PEG Castor Oils are suitable excipients used in both compounding and the pharmaceutical industry and there are multiple examples of commercial injections that are FDA approved for which polyethoxylated castor oils are a component of, such as paclitaxel injection, teniposide injection, docetaxel injection, and cyclosporine injection.

This is true. However, these drugs also have warnings that they can cause hypersensitivity reactions. As I mentioned above, in the case of paclitaxel and docetaxel (both taxanes), patients are premedicated with steroids because the risk of hypersensitivity reactions due to the PEG castor oil excipient is so high.

Imprimis received written documentation from its FDA registered and inspected supplier as to the suitability of its PEG 40 Castor Oil material for use in human compounded products. This documentation, received prior to use of the material, stated specifically, “We certify that our product, P2404 PEG Castor Oil is manufactured, packaged and held in compliance with 21 CFR, Parts 210 and 211 of the United States Code of Federal Regulations and is suitable for pharmacy compounding use.”

OK, Imprimis and the FDA can’t both be correct. Imprimis denies using non-pharmaceutical grade PEG 40 Castor Oil, and the FDA found that it did. I would tend to go with the FDA on this. Basically, Imprimis is blaming its supplier, which, I suppose, is possible, but given all the other negative findings in the FDA inspection last year I’m not about to give Imprimis the benefit of the doubt about anything.

According to federal and state regulations, it is permissible for Imprimis (and any other pharmacy) to use curcumin in human drug compounding (FDA’s 503A Category 1 for Bulk Drugs for Use in Compounding).

I note that this statement, dated July 1, lists curcumin as being nominated for use in compounding under section 503A and lists it among other substances being under evaluation. Seriously, Imprimis, did you really think we wouldn’t click on the link and read the actual FDA document?

Imprimis maintains that the prescriptions it filled for the subject curcumin emulsion vials were valid, labeled properly, and that the curcumin emulsion dispensed was correctly made according to state and federal law.

Given that intravenous curcumin is not FDA-approved for any indication, I find this hard to believe. If true, though, it is a huge glaring problem with the law that sleazy companies like Imprimis exploit.

The Great Yellow Hope diminished

It’s not surprising that naturopaths would be attracted to curcumin as the cure for everything. They love to latch on to natural compounds that show promise in clinical medicine, and it is true that curcumin has been studied widely as a potential cancer treatment, so much so that I used to jokingly refer to it as the “Great Yellow Hope” for cancer. It’s also been studied for inflammatory diseases as well. Indeed, there have been lots of seemingly promising experiments in vitro and in animals published, but clinical trials carried out thus far have been very disappointing. A recent review in the Journal of Medicinal Chemistry was particularly damning:

Curcumin has recently been classified as both a PAINS (pan-assay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. The likely false activity of curcumin in vitro and in vivo has resulted in >120 clinical trials of curcuminoids against several diseases. No double- blinded, placebo controlled clinical trial of curcumin has been successful.

I explained, with the help of Derek Lowe, what PAINS and IMPS compounds are, why curcumin is almost certainly one of these, and further why that means curcumin’s benefits likely will not translate into clinical practice.

Here’s a general rule of thumb, particularly with a compound like curcumin. When clinical studies are this unimpressive and everyone’s scrambling to handwave “alternative explanations” for efficacy, it’s not a good sign. Indeed, the enthusiasm for curcumin among cancer researchers has always puzzled me, given how weak the existing evidence base is for its efficacy and the serious drawbacks it has in terms of solubility, instability, and bioavailability. Naturopaths, as is their wont when looking for legitimacy, take that enthusiasm and turn it up to 11, because the success and adoption of curcumin by conventional medicine would validate their worldview about the usefulness of natural products. It is this worldview that leads to tragedies like the death of Jade Erick.

The fallout

Unfortunately, it appears that naturopaths will never learn. After the death of Jade Erick, naturopaths did what naturopaths always do after one of their own causes harm to a patient through quackery. They circled the wagons and tried to find strategies not to have to take serious disciplinary action against Kelly Kim.

There is, however, a very interesting wrinkle. The California law providing for naturopathic licensure is scheduled to sunset at the end of this year. There is, however, a new bill (SB 796), introduced by Jerry Hill (D-San Mateo) that would extend naturopathic licensure to 2022. The case of Jade Erick would thus seem to represent a dire threat to naturopathic licensure in California. “Seem” is the operative word, sadly. The bill passed the California Senate unanimously in July and appears to be wending its way through the Assembly committee process unimpeded.

Between the government-imposed weakness of the FDA mandated by anti-regulation politicians and the willingness of politicians to keep licensing quackery, I fear there will be more cases like Jade Erick.



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Kim Kelly, ND (Not A Doctor). He prescribed the dose of intravenous turmeric that killed Jade Erick.

Finally, a mystery has been solved.

Nearly five months ago, a 30 year old woman named Jade Erick suffered a cardiac arrest, most likely due to anaphylactic shock, during the infusion of intravenous curcumin ordered by a California naturopath named Kim Kelly, ND (for Not-a-Doctor). Because Erick’s death was so sudden and dramatic, the story briefly made national news. I viewed the tragic incident as yet another example of why “licensed” naturopaths, such as those in California or other states that have made the mistake of passing laws allowing the licensing of naturopaths, are no less likely to mess up your health or even kill you than “unlicensed” naturopaths, such as the naturopath in Bowling Green who was shot by the husband of one of his patients. The reason for the shooting? That naturopath had told the man’s wife that “chemo is for losers” and treated her with the usual naturopathic voodoo, allowing the woman’s cancer to progress until it was no longer treatable with conventional medicine.

Jade Erick didn’t suffer from a life-threatening disease like cancer. She did, however, have a condition that almost certainly significantly affected her quality of life for the worse, namely eczema. Eczema is the name commonly given a group of medical conditions characterized by inflammation of the skin (i.e., rashes). The most common type of eczema is known as atopic dermatitis or atopic eczema, with the “atopic” referring to a group of diseases with an often inherited tendency to develop other allergic conditions. It’s a pretty common condition, too, with around 10% to 20% of infants being affected and around 3% of adults. Most children with eczema “outgrow” it, but some people continue to have symptoms on and off for the rest of their lives. Because eczema’s clinical course can be so varied and intermittent and also because the itching it causes can be very intense, it is a magnet for quacks like naturopaths. There are, of course, conventional medical treatments for eczema that relieve the itching and irritation and prevent rashes, but they leave much to be desired, again another characteristic of diseases or conditions that are quack magnets.

A little over a week ago, a number of readers sent me a link to an FDA safety alert and report of its investigation into Erick’s death and another case of a serious hypersensitivity reaction due to intravenous curcumin. Included with these two links was a link to an alert about the risk of compounding medications. It turns out that what likely killed Jade Erick was a hypersensitivity reaction to the use of a component that wasn’t pharmaceutical grade and is also known to cause hypersensitivity reactions. Let’s take a look.

Jade Erick and the naturopath who killed her

As I mentioned before, Jade Erick was an otherwise healthy 30 year old woman with a chronic medical condition. For whatever reason, however she found him, she sought out treatment from a naturopath named Kim Kelly, who, as it turns out, has been a vocal advocate of intravenous curcumin to treat…just about everything. Indeed, although after Erick’s death Kelly started scrubbing every mention of intravenous curcumin from his website, enough remained to demonstrate his enthusiasm for its use:

I am excited to announce that I’ve started administering intravenous curcumin. Curcumin has been used for thousands of years for culinary and medicinal reasons. People have used it to help with pain, inflammation, immune system, arthritis, liver conditions and cancer. It’s also been found that intravenous curcumin in combination with vitamin C and glutathione (I call it the “Mother of All Antioxidants”) has a potentiating effecting in helping people with chronic health conditions e.g. hepatitis C, liver fibrosis. Intravenous Curcumin is absorbed better, faster and can be given in much higher doses compared to taking it orally. Therefore, the benefits usually can be seen much sooner. Patients who have received it thus far have reported benefits very soon after treatment.

If you are suffering from any type of inflammatory condition, whether it be arthritis, autoimmune condition (e.g. scleroderma, lupus or rheumatoid arthritis), Alzheimers or dementia, this may be a great modality of treatment to try. It may require multiple treatments or may be just one treatment, depending on each person and the condition.

The safety, tolerability, and nontoxicity of curcumin at high doses have been well established by human clinical trials. Promising effects have been observed in patients with various pro-inflammatory diseases.

I can’t help but note that that last statement is absolutely false. Yes, orally administered curcumin is generally pretty safe even up to 8 g per day. However, intravenous curcumin hasn’t been well studied, as I discovered when I started doing more PubMed searches (although I did find a bunch of articles in which investigators were trying to use curcumin nanoparticles, micelles, and the like to administer curcumin IV). This is naturopathic “reasoning,” such as it is: If a little is good, a boatload would be better. Finally, if real medical science is investigating a natural product for one indication and it shows a bit of promise, then to naturopaths it must be a wonder medicine that cures everything—and I do mean everything. Take a look at the list of conditions for which Kelly claims treatment efficacy of IV curcumin:

INFLAMMATORY DISEASES

  • Inflammatory Bowel Disease (Crohn’s and Ulcerative Colitis)
  • Osteoarthritis
  • Post-Operative Inflammation
  • Irritable Bowel Syndrome
  • H. pylori infection

METABOLIC DISEASES:

  • Type 2 Diabetes
  • Diabetic Nephropathy

SKIN:

  • Psoriasis
  • Vitiligo

OTHERS:

  • Beta-Thalassemia
  • Hepatoprotection
  • Alcohol Intoxication
  • Chronic bacterial prostatitis
  • Alzheimer’s
  • Atherosclerosis
  • Arsenic Exposure

Oddly enough, eczema is not on the list. Obviously, “Dr.” Kelly expanded his list before treating Ms. Erick. In any case, it’s always a huge red flag when I see a long list of unrelated diseases and conditions treated by the same drug or treatment. I mean, chronic bacterial prostatitis and atherosclerosis and arsenic exposure? Seriously? In any event, although curcumin has been a favorite of naturopaths for a long time, intravenous curcumin is a relative newcomer on the quack scene. The foremost promoter and popularizer of infusing this compound directly into the veins instead of administering it orally is Paul Anderson, who, as we will see, was so concerned about this death that he issued a disingenuous defense of what Kelly did.

As for Kelly himself, as I like to say, he is everything that organized naturopathy says a good “naturopathic physician” should be. Just look at his profile on his website:

Dr. Kim D. Kelly graduated from Bastyr University in 2001 and is a licensed Naturopathic doctor in the state of California. Growing up on a farm in Northern Minnesota is where he first had experience in the healing power of nature. This was further fostered when reading about the numerous clinical trials using alternative therapies when he was getting his Master’s of Public Health (MPH in Epidemiology) at the University of Minnesota. After realizing the power and effectiveness of alternative therapies, his career goal as Epidemiologist changed to wanting to become a Naturopathic Doctor; thus, he enrolled at Bastyr University in Seattle, WA.

Upon graduation from Bastyr, he underwent a rigorous three year training program at a cutting edge clinic, where he was trained by a team of medical and naturopathic doctors (Nazanin Kimiai, ND, LAc; Dietrich Klinghardt, MD, PhD; David Musnick, MD, MPH). Through his experience at this integrative clinic, Dr. Kelly learned the art and science of progressive healing modalities for musculoskeletal pain, autoimmune conditions, chronic infections (parasites, Lyme, mold), environmental & heavy metal toxicities and general health issues.

Dr. Kelly’s four years as technical director and consultant with Sabre Sciences has given him a strong background on use of bio-identical hormones and neurotransmitters for issues e.g. menopausal and andropause symptoms, PMS, insomnia, anxiety or chronic fatigue. His specialties include adrenal fatigue, thyroid disorders, hormonal issues in men and women (menopause, andropause, PMS, etc.), musculoskeletal pain and heavy metal detoxification. A lot of his practice also involves a technique called Biopuncture to help with chronic pain, headaches, gastritis, IBS and other health issues (See Service List for more details). He currently has an office in Encinitas.

Dr. Kelly has lectured locally and nationally on topics e.g. hormone balance for men and women, heavy metal toxicity and what we can do, nutritional research on Autism, gastrointestinal issues and natural medicine in San Diego.

In the world of naturopathy, Bastyr is the equivalent of Harvard or Stanford. Of course, being the Harvard or Stanford of quack schools is not saying much. After all, Bastyr recently sent a cease-and-desist letter to Britt Hermes, a former naturopath who graduated from Bastyr but eventually came to the realization that naturopathy is pure quackery and has been unrelentingly critical of her former alma mater ever since. My point, of course, is that Kelly graduated from what groups like the American Association of Naturopathic Physicians (AANP) view as the crème de la crème of naturopathy schools and is fully licensed in the largest state in the country. Of course, I can’t help but note that in his bio asserting his pseudoprofessional bona fides, he can’t help but mention one of naturopaths’ favorite forms of quackery, “heavy metal detox.” I find that appropriate.

Perusing the rest of Kelly’s website, even without the benefit of the almighty Wayback Machine at Archive.org, which rescues web pages from the memory hole every day, I found plenty of quackery offered by his practice. For instance, he offers biopuncture, naturopathic detoxing, hormonal balance treatment, IV nutrition, and “wellness programs.” Biopuncture, I note, is an unholy combination of acupuncture and homeopathy so quacky that Dr. Oz promoted it. Kelly describes it thusly:

Biopuncture is a technique that combines neural therapy, trigger point therapy, prolotherapy and homotoxicology. It stimulates the body’s own healing mechanisms thus speeding up the process of injury recovery, natural rejuvenation/repair and also lowers pain and inflammation. The technique involves using pin-prick needles to inject miniature amounts of homeopathic remedies under the skin or into muscle encouraging the body to start healing and to help stimulate local blood circulation.

In other words, it’s some most excellently ridiculous woo, a witches’ brew of quackery, to go along with all the other nonsense in Kelly’s blog, such as (of course) more biopuncture and more “detoxification,” along with other quackery such as adrenal fatigue treatment, intravenous vitamin C, and a dangerous modality like intravenous peroxide for chronic infections. All of this costs only $150 per 30 minutes plus the cost of the therapy.

Not surprisingly, when a real medical emergency happened right in his own office, “Dr.” Kelly wasn’t prepared to deal with it. The result is described in the FDA report:

On March 10, 2017, the U.S. Food and Drug Administration received an adverse event report concerning a 30-year-old female patient who experienced cardiac arrest after IV administration of a curcumin emulsion product compounded by ImprimisRx. The patient reportedly had a history of allergies and was being treated for eczema by a naturopathic doctor. Within minutes of starting the infusion, the patient became pulseless and required CPR. The patient suffered anoxic (depleted oxygen) brain injury and subsequently died. An adverse reaction to infused curcumin solution was identified as a cause of death by the local authorities.

So what caused the hypersensitivity reaction that killed Jade Erick within minutes of the start of her infusion of IV curcumin? The FDA thinks it’s found the cause both of her death and of a similar hypersensitivity that nearly killed a 71 year old man who was being treated for thrombocytopenia (a low platelet count) at a holistic health center. Amazingly, that “holistic” health center appears to have actually had medications to deal with an acute anaphylactic reaction, which kept him alive long enough to get him to an emergency room. In fairness, Erick’s reaction appears to have been so fast that there might not have been time to administer diphenhydramine and epinephrine.

Beware compounding pharmacies that play fast and loose with ingredients

In response to the reports of Jade Erick’s sudden death, the FDA did what the FDA does very well. It investigated. It turns out that the intravenous curcumin emulsion used was manufactured by ImprimisRx Pharmaceuticals, a compounding pharmacy based in San Diego, California. There are, of course, legitimate compounding pharmacies, and such pharmacies serve a useful role in medicine, but there are also a lot of compounding pharmacies that cater to naturopaths, mixing up combinations of supplements, “natural” medications, and the like for that particular market. ImprimisRx appears to be one such pharmacy, manufacturing both legitimate FDA-approved drugs and compounds like its Curcumin Emulsion MDV and, of course, intravenous vitamin C. It also manufactures intravenous EDTA for chelation therapy.

The FDA collected samples from the IV bag used to dose Jade Erick and from the ImprimisRx curcumin emulsion vial used to prepare the IV bag. It also analyzed the samples of ImprimisRx’s curcumin emulsion product and identified the presence of certain contaminants and impurities. It found a number of rather interesting (and disturbing) things. First, the FDA noted that there wasn’t nearly as much curcumin in ImprimisRx’s curcumin emulsion product as claimed on the labeling. The solution in the IV bag contained only 2.34 μg/mL of curcuminoids, which is only around 1% of the curcumin concentration intended to be administered. It also found that the concentration in the emulsion vial contained only around 0.205 mg/mL of curcuminoids, which is less than 2% of the curcumin concentration represented on the label. One of the big problems with administering curcumin is that it undergoes rapid degradation at physiologic pH, and that might explain why the concentration of curcumin in the vial was so much lower than what was represented on the label. Of course, a good compounding pharmacy should know these issues and limitations and take steps to mitigate them. Clearly ImprimisRx did not. As a result, Kelly and all the naturopaths who thought they were giving their patients “high dose” curcumin were probably giving them less than what a patient would get by taking curcumin supplements orally.

More importantly and relevant to what caused Jade Erick’s death, the FDA found this:

FDA collected and analyzed samples of PEG 40 castor oil from the same lot of ImprimisRx curcumin emulsion product that was administered to the female patient. FDA identified 1.25% w/w DEG [diethylene glycol] in the PEG [polyethylene glycol] 40 castor oil. The label of the tested PEG 40 castor oil includes the warning “CAUTION: For manufacturing or laboratory use only.” The PEG 40 castor oil used by ImprimisRx was ungraded, and not, for example, pharmaceutical grade or food grade. Ungraded products are suitable for general industrial or research purposes and typically are not suitable for human consumption or therapeutic use. There is no U.S. Pharmacopeia (USP) monograph for PEG 40 castor oil.

The FDA notes that drugs, including FDA-approved products, containing polyethylene glycol castor oil have been “associated with severe and sometimes fatal hypersensitivity reactions and include warnings about these reactions in their labels.” One example IV paclitaxel containing Cremophor® EL (PEG 35 castor oil), which can cause severe hypersensitivity reactions in up to 20% of patients. That’s why patients receiving paclitaxel are premedicated with steroids, and it’s why a new formulation lacking the PEG 35 castor oil, Abraxane, is coming into wider usage. The FDA further noted:

Some of the other ingredients in ImprimisRx’s product, including curcumin, also have been associated with hypersensitivity reactions when administered intravenously. There are reports of contact allergies to a metabolite of curcumin, tetrahydrocurcumin, for instance. In addition, there is little to no toxicologic or clinical information available regarding the safety of IV curcumin, and evidence is lacking that curcumin is an effective therapy for eczema or thrombocytopenia. There are no FDA-approved curcumin for injection products.

The ungraded PEG 40 castor oil in ImprimisRx’s curcumin emulsion product may have contained components that resulted in the hypersensitivity reactions. Castor bean seeds and pollens are known to be associated with hypersensitivity reactions. Food grade castor oil is processed to remove the potentially allergenic castor bean constituents, but ungraded PEG 40 castor oil may not be allergen free. In addition to allergens, other potentially harmful contaminants and impurities could be present in the ungraded PEG 40 castor oil.

It was also noted that DEG is a central nervous system depressant, as well as a potent kidney and liver toxin that can cause kidney failure. It’s commonly used in industrial products like antifreeze and brake fluid.

The FDA concluded:

FDA’s investigation into the adverse events associated with ImprimisRx’s curcumin emulsion product for injection highlights some of the risks associated with compounded drugs, particularly those that use non-pharmaceutical grade components and ingredients lacking a USP monograph. The risks illustrated in this case include:

  • the absence of a label warning about hypersensitivity reactions associated with the PEG 40 castor oil;
  • the use of an ungraded inactive ingredient, i.e., PEG 40 castor oil, that is not suitable for human consumption or therapeutic use and may contain impurities such as DEG; and
  • the IV administration of curcumin, despite the fact that its safety profile by this route of administration has not been established, nor has its effectiveness in treating eczema or thrombocytopenia.

So basically, it appears from the FDA report that a perfect storm of woo killed Jade Erick: A naturopath using an unproven treatment plus a compounding pharmacy cutting corners manufacturing its products using PEG 40 castor oil that wasn’t pharmaceutical grade and failing to place a warning label on its curcumin emulsion warning that components of the emulsion can cause hypersensitivity reactions. According to the FDA, ImprimisRx recalled its unexpired products containing the ungraded castor oil on June 23, 2017, which was over two months after the second hypersensitivity reaction (in the 71 year old man) was reported.

The danger of some compounding pharmacies

Another lapse in this case included that there was no prescription for the IV curcumin found. At least, the company told a media outlet that it did not have a prescription. Britt Hermes, in her discussion of the case, speculated based on her experience as a naturopath about how such a thing might have happened and how Kelly might have obtained the curcumin for Erick without a prescription:

Kelly may have used a vial of the curcumin emulsion that was obtained under a prescription for another one of his patients. My former naturopathic colleagues in Arizona at times purchased compounded products in bulk for a single patient to then be used for multiple patients. This stockpiling allowed naturopathic doctors to have compounded drugs on-hand, thereby expediting treatments for multiple patients using only one prescription. Or, Kelly may have obtained the curcumin emulsion from a physician or another naturopathic doctor who had product on hand for their own patients. The borrowing of medical supplies, including compounded substances, is a common practice in the naturopathic community. Either way, using a prescription of one patient for another patient is not permitted by the FDA.

Worse, this sort of occurrence can’t be said to have been entirely unexpected, given ImprimisRx’s previous run-in with the FDA. Last year, the FDA inspected ImprimisRx’s manufacturing facility in Pennsylvania and found a number of violations. These included failures to test:

  • aqueous solutions and suspensions or encapsulated powders to determine if they meet specifications for the intended, labeled dose of active drug ingredient
  • products intended for inhalation to verify that the particle size is correct
  • inhalation products for microbial contamination
  • products to determine appropriate expiration dates

The inspection also found that there were “no written procedures for production and process controls to assure that the drug products have the identity, strength, quality, and purity they purport or are represented to possess,” which likely explains a lot about how the curcumin emulsion could have a potency of only 2% of what was claimed on the label, especially since the FDA found a number of other lapses indicating what can only be called a lack of concern for preventing bacterial contamination and assuring that what is in the product matches what the label says.

Compounding pharmacies can play an important role in medicine. For instance, special compounding might be required if a patient needs a medication to be made without a certain dye or inactive ingredient because of an allergy or needs a medication in liquid or suppository form that is not manufactured in such forms. Unfortunately, a lot of companies go beyond such needs, as the FDA noted in a recent article on compounding pharmacies:

“Some aspects of these firms’ operations appear more consistent with those of drug manufacturers than with those of traditional pharmacies,” says Bernstein. “Some firms make large amounts of drugs that appear to be copies of FDA-approved, commercially available drugs when it does not appear that there is a medical need for an individual patient to receive a compounded version of the drug.”

The FDA also expressed concerns about compounding pharmacies just this year, noting serious incidents linked with them. Most of these incidents have to do with contamination with microorganisms. For instance, in 2012, there was an outbreak of fungal meningitis linked to an injectable steroid medication manufactured by a compounding pharmacy. In 2011 and 2012, 33 eye surgery patients in seven states suffered a rare fungal infection of the eye linked to injectable drug products, resulting in partial to severe vision loss, while in 2011 repackaged injections of Avastin (bevacizumab) also caused serious eye infections in the Miami area. These latter two incidents resulted in serious vision loss in some patients. Some patients injected with the contaminated Avastin lost the remaining vision in the eye being treated.

It’s stories like this that make me laugh derisively any time I hear a politician complain about FDA “overreach.” In reality, the reason these sorts of incidents occur with a distressing regularity is because the FDA is underfunded and understaffed. It has a hard time overseeing pharmaceutical company manufacturing facilities adequately, much less compounding pharmacies, allowing compounding pharmacies like ImprimisRx to continue doing business. Indeed, look at Imprimis Pharmaceuticals’ (IMMY) statement regarding the FDA’s findings. Basically, the company is trying to shift the blame for Jade Erick’s death from its product to…well…anyone else.

For example:

Imprimis had no knowledge of the allergy histories of the subject patients.

So what? Imprimis manufactured a product with components known to cause acute hypersensitivity reactions, and there was no warning of this on the product label.

FDA testing of the IV bag from the 30 year-old patient revealed “no drugs or poisons including diethylene glycol [DEG] at a level greater than 0.1% by volume, were identified in the IV bag contents using GC-MS.” We believe that evidence thus far does not support the 30 year-old patient’s death being caused by PEG 40 Castor Oil or DEG.

WTF? 0.1% is a high concentration for “drugs or poisons.” Basically, it’s one part in a thousand. This is not something that strikes me as exonerating Imprimis. Quite the contrary. It suggests that the FDA was quite correct about Imprimis’ shoddy manufacturing if “drugs or poisons” other than what was supposed to be in the product were present at a concentration as high as 0.1% Again, WTF?

PEG Castor Oils are suitable excipients used in both compounding and the pharmaceutical industry and there are multiple examples of commercial injections that are FDA approved for which polyethoxylated castor oils are a component of, such as paclitaxel injection, teniposide injection, docetaxel injection, and cyclosporine injection.

This is true. However, these drugs also have warnings that they can cause hypersensitivity reactions. As I mentioned above, in the case of paclitaxel and docetaxel (both taxanes), patients are premedicated with steroids because the risk of hypersensitivity reactions due to the PEG castor oil excipient is so high.

Imprimis received written documentation from its FDA registered and inspected supplier as to the suitability of its PEG 40 Castor Oil material for use in human compounded products. This documentation, received prior to use of the material, stated specifically, “We certify that our product, P2404 PEG Castor Oil is manufactured, packaged and held in compliance with 21 CFR, Parts 210 and 211 of the United States Code of Federal Regulations and is suitable for pharmacy compounding use.”

OK, Imprimis and the FDA can’t both be correct. Imprimis denies using non-pharmaceutical grade PEG 40 Castor Oil, and the FDA found that it did. I would tend to go with the FDA on this. Basically, Imprimis is blaming its supplier, which, I suppose, is possible, but given all the other negative findings in the FDA inspection last year I’m not about to give Imprimis the benefit of the doubt about anything.

According to federal and state regulations, it is permissible for Imprimis (and any other pharmacy) to use curcumin in human drug compounding (FDA’s 503A Category 1 for Bulk Drugs for Use in Compounding).

I note that this statement, dated July 1, lists curcumin as being nominated for use in compounding under section 503A and lists it among other substances being under evaluation. Seriously, Imprimis, did you really think we wouldn’t click on the link and read the actual FDA document?

Imprimis maintains that the prescriptions it filled for the subject curcumin emulsion vials were valid, labeled properly, and that the curcumin emulsion dispensed was correctly made according to state and federal law.

Given that intravenous curcumin is not FDA-approved for any indication, I find this hard to believe. If true, though, it is a huge glaring problem with the law that sleazy companies like Imprimis exploit.

The Great Yellow Hope diminished

It’s not surprising that naturopaths would be attracted to curcumin as the cure for everything. They love to latch on to natural compounds that show promise in clinical medicine, and it is true that curcumin has been studied widely as a potential cancer treatment, so much so that I used to jokingly refer to it as the “Great Yellow Hope” for cancer. It’s also been studied for inflammatory diseases as well. Indeed, there have been lots of seemingly promising experiments in vitro and in animals published, but clinical trials carried out thus far have been very disappointing. A recent review in the Journal of Medicinal Chemistry was particularly damning:

Curcumin has recently been classified as both a PAINS (pan-assay interference compounds) and an IMPS (invalid metabolic panaceas) candidate. The likely false activity of curcumin in vitro and in vivo has resulted in >120 clinical trials of curcuminoids against several diseases. No double- blinded, placebo controlled clinical trial of curcumin has been successful.

I explained, with the help of Derek Lowe, what PAINS and IMPS compounds are, why curcumin is almost certainly one of these, and further why that means curcumin’s benefits likely will not translate into clinical practice.

Here’s a general rule of thumb, particularly with a compound like curcumin. When clinical studies are this unimpressive and everyone’s scrambling to handwave “alternative explanations” for efficacy, it’s not a good sign. Indeed, the enthusiasm for curcumin among cancer researchers has always puzzled me, given how weak the existing evidence base is for its efficacy and the serious drawbacks it has in terms of solubility, instability, and bioavailability. Naturopaths, as is their wont when looking for legitimacy, take that enthusiasm and turn it up to 11, because the success and adoption of curcumin by conventional medicine would validate their worldview about the usefulness of natural products. It is this worldview that leads to tragedies like the death of Jade Erick.

The fallout

Unfortunately, it appears that naturopaths will never learn. After the death of Jade Erick, naturopaths did what naturopaths always do after one of their own causes harm to a patient through quackery. They circled the wagons and tried to find strategies not to have to take serious disciplinary action against Kelly Kim.

There is, however, a very interesting wrinkle. The California law providing for naturopathic licensure is scheduled to sunset at the end of this year. There is, however, a new bill (SB 796), introduced by Jerry Hill (D-San Mateo) that would extend naturopathic licensure to 2022. The case of Jade Erick would thus seem to represent a dire threat to naturopathic licensure in California. “Seem” is the operative word, sadly. The bill passed the California Senate unanimously in July and appears to be wending its way through the Assembly committee process unimpeded.

Between the government-imposed weakness of the FDA mandated by anti-regulation politicians and the willingness of politicians to keep licensing quackery, I fear there will be more cases like Jade Erick.



from ScienceBlogs http://ift.tt/2uTJhly

Comments of the Week #172: From sodium-and-water to the most dangerous comet of all [Starts With A Bang]

“Life is not a miracle. It is a natural phenomenon, and can be expected to appear whenever there is a planet whose conditions duplicate those of the Earth.” ―Harold Urey

It’s been yet another fascinating week of scientific stories here at Starts With A Bang! But as of the last 48 hours, there’s something I absolutely have to talk about: the “Unite The Right” hate rally in Virginia, accompanied by violence and murder. They say that in order for evil to triumph, all that you need is for good people to stand by and do nothing. When I was a kid — small, young, weak, inexperienced — I saw lots of people get beaten up, taken advantage of, mugged, robbed… and I didn’t do anything. Why? Because I was afraid for myself, for what would happen to me if I did. But I look at the world now, and I see it differently: what happens to us all if I don’t do anything? What happens if none of us stop this madness? It’s time to stand up alongside one another and demand equal treatment, legally, for everyone.

We live in a country where a black man will be criticized and even blacklisted from his job for taking a knee during the national anthem because he’s making a statement about equal rights and protections under the law, but the rights of neo-nazi murderers to hatch terrorism plots and violently attack counter-protesters (two pretty illegal things, by the way) are not even addressed by our country’s leadership. In 2017, more than 70 years after the world united to defeat fascism and white supremacy and oppression, actions like these are not condemned by the president. My grandfathers fought those Nazis, alongside the rest of the free world. It is up to every one of us — whether we’re white or persons of color; whether we’re men, women, or non-binary; whether we’re Christian or not; whether we’re cis or straight or citizens or not — to recognize that we’re all human beings, and that we have every right to demand those same human rights: life, liberty, and the pursuit of happiness. That is what America is about.

The (public domain) State Flag of Virginia. No joke.

Virginia, you have the most hateful state flag in the entire country. You changed it in 1861, after you seceded, to make it about murdering what you perceived as a tyrannical leader, in a Shakespearian scene. Four years later, theatre actor John Wilkes Booth did exactly this, acting out a scene from his favorite play in a way, murdering Lincoln the same way Brutus and Cassius murdered Caesar. Those three infamous words, sic semper tyrannis, are from Shakespeare, are emblazoned on the Virginia flag, and were shouted by Booth as he shot Lincoln in the head. We have a long heritage of hate, slavery, and murder in this country, and it is up to all of us to renounce rather than celebrate these awful parts of our nation’s past. We are moving forward, and no amount of hatred or demonization or violence is going to solve any of our nation’s problems. We will fight this hate with our words, with our bodies, and if necessary, with our lives. And in the end, just like always, hate will lose.

I had to say that. I cannot stand by and only talk about science when there are these other atrocities happening right here. It’s time to make a difference. It’s time to get involved. And it’s time to speak out. Nazis cannot make us afraid, and everyone needs to know that all of America is united against this hate. Even if the President is silent about it.

With that said, let’s get into the science. There’s been a lot to explore, question, and go over, despite all the things we disagree with one another on. Thankfully, there are scientific truths that, whether we agree with one another or not, are all true nonetheless. (And thank you to those who left positive comments over the last week. I came, I saw, I appreciated!) Here are the six stories we’ve told that have given you plenty to think about over the past week:

I’ll tell you all that there are at least three new podcasts coming out where I’m a guest — all related to Treknology, as far as I know — and for those of you who’ll be down at Brooks Winery in Salem next Sunday and Monday for the total solar eclipse, I’ll see you there! With all that said and done, let’s get right into our comments of the week!

32 images of the 2016 eclipse were combined in order to produce this composite, showcasing not only the corona and the plasma loops above the photosphere with stars in the background, but also with the Moon’s surface illuminated by Earthshine. Image credit: Don Sabers, Ron Royer, Miloslav Druckmuller.

From Michael Hutson on why eclipse science is still important: “Why is ground observation of total eclipses still so important when we have had manned and unmanned observation from orbit for decades?”

It’s absolutely true that we have space-based observation of the Sun and its corona; we’ve used radio astronomy to measure the shifting positions of stars over the course of a year; we’ve used gravitational lenses to better test and constrain relativity; and it’s things like stereographic satellite imagery and lunar laser ranging that have enabled us to determine the shape of the Moon’s shadow on Earth. Yes, the vast majority of scientifically useful eclipse data is historic, from validating relativity to measuring the coronal temperature and nature to the discovery of plasma loops to coronal mass ejections.

More than 2/3 of the American population is within a single day’s driving distance of the path of totality. This could create the worst traffic jam in American history. Image credit: Michael Zeller / greatamericaneclipse.com.

But there are still things we can do from the ground that have advantages, particularly the ones that are Earth-related. The uninterrupted land mass that this eclipse will pass over allows for the opportunity to understand atmospheric and temperature changes, the relationship between the Moon’s shadow and phenomena here on Earth’s surface, and the short-term but continuous variation in the Sun’s luminosity. Yes, we can do many things better from space, but we live here on Earth, and there’s still more science to be done!

A room where the walls, even if completely covered with mirrors, would never have every location illuminated, was a mathematically interesting conjecture that was only solved recently. Image credit: Mathematical Sciences Research Institute (MSRI) / Numberphile / Brady Haran / Howard Masur.

From dean on how certain problems in math have incremental progress made towards them: “More directly, a slightly simpler version may be attacked first, with interest as much on the process used to solve it as the solution. As restrictions on the problem statement are weakened work (often) goes to modifying what worked earlier in hopes on the more general problem.”

This is true, and is quite a precise and laudable statement. We do this in physics, too, except in physics we simplify deliberately. Think about what you’d need to know to successfully model a physical system accurately: the physical properties of all the particles in the Universe, relative to one another, their interrelationships and entanglements, and all the forces between them, as well as how it all evolves over time in a well-defined, relativistic and quantum context. Sounds like a tall order, doesn’t it?

The big strength of physics is its ability to simplify. The strength of physicists is in modeling: in knowing how to chew on the meat and throw away the bones of the problem. If you can boil down a problem to its key essence and solve that simplified version, that’s huge. If you could take the entire Universe and simulate all the physical interactions taking place, it would be interesting, too, but it would take a computer with the computing power of the entire Universe to do it, and it wouldn’t teach you anything new. Relating equations, theories, and models to physical phenomena is where it’s at.

The fabric of spacetime, illustrated, with ripples and deformations due to mass. A new theory must be more than identical to General Relativity; it must make novel, distinct predictions. Image credit: European Gravitational Observatory, Lionel BRET/EUROLIOS.

The fabric of spacetime, illustrated, with ripples and deformations due to mass. A new theory must be more than identical to General Relativity; it must make novel, distinct predictions. Image credit: European Gravitational Observatory, Lionel BRET/EUROLIOS.

From CFT on a perceived weakness in relativity: “…there is no known solution to even TWO masses (much less more than two) in the same space time matrix. That’s not a little thing to gloss over like a minor typo.”

Nope; it’s a testament to how complicated and intricate a theory like General Relativity is. But just because we can model a system that is too difficult to solve exactly (or analytically) doesn’t mean it’s any less valid. Reread that last sentence a few times; if you can absorb the information in it, you’ll understand why your argument for the “wrongness” of relativity (or the Navier-Stokes equation, or pretty much any complex physical system) holds no water.

Signs and protesters from the 2013 March Against Monsanto in Vancouver, BC. While there may be legitimate complaints over our modern agricultural system, GMOs are not the evil technology that people make them out to be. Image credit: Rosalee Yagihara of Wikimedia Commons.

From John on making a difference in science: “The subjective portion is deciding what parts of Science are “fringe”.”

This is true, and I fully admit that I have my own opinions on that matter. I am aware that although there are objective criteria in there, all of the ones I use are not (and cannot be, by their nature) objective. The danger comes when we present a subjective criterion as an objective one, and that’s something we’re all at risk for. I hope you enjoyed my review of the Little Black Book of Junk Science, whose authors have a right-wing bias, but that doesn’t make the science they present any less valid. It’s important to consider views that challenge our own, otherwise we’ll never learn anything new or be open to possibilities that are foreign to us.

In warm-weather years, which are statistically more likely with global warming, large, more powerful hurricanes, like 1985's Hurricane Elena, are more likely, but there will be fewer of them. Image credit: Image Science and Analysis Laboratory, NASA-Johnson Space Center.

In warm-weather years, which are statistically more likely with global warming, large, more powerful hurricanes, like 1985’s Hurricane Elena, are more likely, but there will be fewer of them. Image credit: Image Science and Analysis Laboratory, NASA-Johnson Space Center.

From Paul Dekous on Hurricane Elena: “Damn, I thought you were using that Hurricane Elena image on top of the page to answer how ‘Black Holes’ at the center of large galaxies could be voids.”

Nope, just to talk about hurricanes and other weather-based natural disasters. Black holes can’t really be “voids” in any meaningful sense, but the similarities between an “eye” of a storm and the cloud bands and an event horizon of a black hole and its accretion disk can be visualized in an analogous fashion. I’d say that’s fair!

The stars within and beyond the Pillars of Creation are revealed in the infrared. While Hubble extends its view out to 1.6 microns, more than twice the limit of visible light, James Webb will go out to 30 microns: nearly 20 times as far again. Image credit: NASA, ESA/Hubble and the Hubble Heritage Team.

From Brian K. Grimm on why we can’t all just get along: ” I do not understand the type of people that can look at a suite of scientific data, then pull specific corner cases from that data and say ‘all these hundreds of other analyses can’t be right, because of this one.’ I don’t just see it in physics either. I see it in finance/economics, politics, history, and religious discussions. Why is it so hard to agree on what reality is?”

I’m not a psychologist, and I don’t know that psychologists — even the ones that study bias and the Culture Wars — have the answer, so what you’re getting from me is a guess. My guess is that, for some people, particularly when it comes to some topics, getting a specific answer or reaching a specific conclusion is more important than those other things. If it’s part of your very identity that the world be flat, then your options are either to accept a round Earth and deny your core identity, or to hold onto your core identity and insist that the world is flat… and that’s when the logical and rhetorical gymnastics enter.

Some people love that game: the arguing and the argument-crafting, but I’m not one of them. I’d rather just earnestly ask after the truth, find the best answers we can arrive at, and share those results. Those of you who find your core identity in disagreement with my own (or what you perceive my own to be) will find an avenue to attack that too, but don’t worry. By this time next year, I’ll be 40, which, according to Mike Gundy, means I’ll be able to take the heat.

An artist’s impression of the three LISA spacecraft shows that the ripples in space generated by longer-period gravitational wave sources should provide an interesting new window on the Universe. LISA was scrapped by NASA years ago, and will now be built by the European Space Agency, with only partial, supporting contributions from NASA. Image credit: EADS Astrium.

From Michael Mooney on the ridiculousness of relativity: “I pointed out how totally ridiculous that claim is.”

Well, to someone who’s unwilling to accept the Universe as it is, the Universe is ridiculous. Electricity is ridiculous; gravitation is ridiculous; motion is ridiculous; and just wait until you get to quantum physics. It is not up to the Universe to bow to your claims of what makes sense and what doesn’t; the Universe does what it does and it’s up to us to decode how that works, and what predictions we can make in a variety of physical scenarios. Relativity has been doing that, correctly, for over 100 years. You are an onlooker, pointing and laughing, all the while reaping the benefits of relativity. Try using a GPS device (if you can find one) that doesn’t use relativity, and see how that works for you; you won’t like it.

Image credit: ESO / L. Calçada.

This artist’s impression shows the magnetar in the very rich and young star cluster Westerlund 1. Image credit: ESO / L. Calçada.

From eric on the “z” of a neutron star: “Unless that neutron star is in a *very* empty region of space, there will be a constant infallinng of particles. If the stuff falling in has protons (and it probably will), there will be some time required for those protons to be converted.”

Oh, you don’t need to go there! A neutron star only has about 90% of its mass in the form of neutrons; the outer 10% of its mass is more like a mix of protons, neutrons and even electrons. There ought to be atoms on a neutron star’s surface. Without those charged particles, you’d never be able to get a magnetic field in your neutron star, and yet they have the strongest magnetic fields in the Universe! The question, though, is whether it’s fair to consider the entire star as a single nucleus, or only a fraction of the core, and I think it’s the latter. But I am uncertain that the matter has been scientifically settled.

The increased emission of greenhouse gases, notably CO2, can have a massive impact on Earth’s climate in just a few hundred years. We’re witnessing that happen today. Image credit: U.S. National Parks Service.

From Another Commenter on a challenge to the climate consensus: “Herer’s (sic) an interesting news item about of reliable the data is from the signatories to Paris Climate Accord.
http://ift.tt/2uB7HzV

That is interesting. What it says, for those who won’t read it, is that a number of nations may be lying about what their actual emissions are versus their reported emissions. Veritas, my friends.

A remote camera captures a close-up view of a Space Shuttle Main Engine during a test firing at the John C. Stennis Space Center. Hydrogen is preferred as a fuel source in rockets due to its low molecular weight and the great abundance of oxygen in the atmosphere for it to react with. Image credit: NASA.

From Alan G. on calling out my rocket fuel caption: “The rocket engine photo caption is curious. Rocket engines don’t use atmospheric gaseous oxygen when running. They have to carry all of their own oxidizer with them also, along with their fuel.”

I’m impressed at how diligent you were to catch this! Yes, in principle, there’s a great abundance of oxygen in the atmosphere, and if you had O2 intake, you could react it with the hydrogen fuel inside.

But in practice, the act of taking in oxygen to react with the hydrogen will cost you more in terms of air resistance and the collisions of particles at those high relative speeds (plus your lack of ability to control the reaction rate as you went to low-oxygen elevations) means that it’s better to bring your oxygen liquid fuel with you, too. Well spotted, and thanks for coaxing me to go the extra mile!

A plume of smoke from wildfires burning rises over Fort McMurray in this aerial photograph taken in Alberta, Canada. The entire Pacific Northwest region of North America is suffering from severe wildfires, and the season hasn’t even peaked yet. Image credit: Darryl Dyck/Bloomberg.

From PJ on wildfires in Oregon: “Would need to get the good words of warning out to the general public and overseas travelers who may not be aware of the local conditions.”

Between the fires, the unpredictable winds, and cloud cover — including the haze cover from smoke in the copious Canada wildfires — a great many locations in the three westernmost states to see the 2017 eclipse will be at risk of having the Sun obscured during totality. Going to the coast may not solve the issue, either. Like over a million others, I’ll be rolling the dice a week from Monday!

Relic microbes revealed by a scanning electron microscope in the ALH84001 meteorite, which originated on Mars. It is unknown whether the microbes are of Martian origin or not. Image credit: NASA, 1996.

From jvj on wanting to be NASA’s planetary protection officer: “I’m perfect for the job. Have seen all the Star Trek TV shows & movies. I enjoy giving orders to menials. Our motto: “We come in Peace.” We can enslave any life forms we find & dig up all the diamonds & gold & drill for oil everywhere on each planet we take over.”

The great danger of contamination is a real one, and it may have already taken place naturally. Do you see this image above? That’s a fragment of a meteor that came from Mars, but it was found on Earth. When you get a massive impact from space on a rocky world — planet, asteroid, moon, or Kuiper belt object — it kicks up debris that can sometimes go back into space and travel to another world. If we find Mars rocks on Earth, does it not stand to reason that Earth rocks made their way to other worlds in the Solar System, too?

It’s worth thinking about, because despite our best efforts to decontaminate our spacecraft before we send them out exploring (and we may have failed at that with our earlier missions to Mars, for example), it may already be too late.

Correctly calibrated satellite data, as well as the more recent temperature data up through 2016, shows that climate predictions and observations are perfectly in line with one another. Image credit: HadCRUT4.5, Cowtan & Way, NASA GISTEMP, NOAA GlobalTemp, BEST, via Ed Hawkins at Climate Lab Book.

From Denier on a nice try: “First of all, you should at least be honest about what you are trying to do. You are trying to de-platform scientific evidence that fails your personal political litmus test. It has nothing to do with ‘good’ science. Santer (2017) is good science. Nature thinks so. You summarily dismissed it without reason. You simply didn’t like what it said. It didn’t support your political narrative so you wished it into the corn field.”

It is a nice try. I appreciate the thoughtfulness of the argument you made, because it’s a well-crafted narrative and it’s very compelling. And yes, I agree that Santer et al. (2017) is good science; Santer is one of the top scientists in the field of climate science. But, as always, what I’ve urged you to do in climate arguments is to be quantitative. Yes, the paper itself says that near-term, recent warming has been overestimated, elucidated why, and quantified by how much. It seems we’re in agreement there.

So tell me, then, how much has the warming been overestimated by the models? What percentage of the models overestimated the warming, before the Santer paper came out? (Hint: it’s less than the 95% that Heartland and UAH claimed, which is a claim that you defended, and which is data that you referenced, repeatedly, claimed was accurate, and never backed down from.) How well do the models do now that they have this improvement?

Yes, I didn’t address it, because it was a small contribution that has only mild relevance to a much larger story. You are crafting a narrative of “Ethan is dismissing evidence because he doesn’t like what it says” when in fact that is what I have witnessed not only you but literally everyone saying the same things as you doing for more than two decades now. (History tells me it may be longer than that, but I wasn’t really aware of the basic scientific story until the mid-1990s.) This is the Trump strategy — accuse your opponents of doing the exact thing you’re guilty of — and it worked for him. You add in the strategy of “focusing on the one factual detail where you are correct, exaggerate its importance, and try to derail the rest of the argument.”

Daffy Duck is smart enough to see what’s going on in a situation, but never figures out how to control what happens.

I feel like Daffy Duck in this situation. You know those old Warner Bros. cartoons with Bugs, Daffy, and Elmer Fudd? Elmer Fudd is not only unable to control the situation, but he’s unable to comprehend it, and always comes out on the losing side. Bugs understands the situation, and is able to manipulate the situation to his advantage; he controls it. Daffy is a tragicomic figure, though, who understands the situation but finds himself unable to control it, even though he sees how Bugs is manipulating it and hates the unfairness of it all. Who knows? You’re fighting your battle in the court of public opinion, and you’re a lawyer. Maybe it’ll work for you, too?

But irrespective of that, I will give you mad props for reading Gavin Schmidt and Ben Santer; their work is top notch. You and I may always disagree on policy, but if you’re reading their work, we may someday wind up agreeing on the facts.

This illustration of a black hole, surrounded by X-ray emitting gas, showcases one of the major ways black holes are identified and found. Based on recent research, there may be as many as 100 million black holes in the Milky Way galaxy alone. Image credit: ESA.

This illustration of a black hole, surrounded by X-ray emitting gas, showcases one of the major ways black holes are identified and found. Based on recent research, there may be as many as 100 million black holes in the Milky Way galaxy alone. Image credit: ESA.

From Omega Centauri on black holes in the Milky Way: “Those are remarkably large numbers. I would think the dwarf galaxies would resemble (in terms of metalicity and BH mass spectrum), the early larger galaxies. In the later category, have enough non-so-low metalicity stars formed to overwhelm the initial distribution?”

That’s part of what’s so exciting; dwarf galaxies aren’t similar to the Milky Way. Bigger galaxies have:

  • larger gas fractions (because the gas doesn’t get ejected during star formation),
  • more generations of stars (because of more major and minor mergers),
  • higher mass stars (because of more mass available, on average),
  • but higher metallicity (because of more generations and more mass),
  • so their high-mass stars shed more mass during their lives,

leading to smaller but far more numerous black holes. There are, if you’re curious, about ten times as many neutron stars as black holes in each galaxy.

Front cover of the hard copy of the Little Black Book of Junk Science. Image credit: American Council on Science and Health.

From Christopher Winter on Junk Science and ideology: “Having read Science Left Behind, of which Alex [Berezow] is co-author with Hank Campbell, I would be very reluctant to put credence in this book. The negative review on Amazon calls it “A pseudoscientific attempt to debunk pseudoscience.” That’s about what I’d expect.”

People with different ideologies than you will, in fact, take the same facts, the same data, and pick out different points to highlight that are still true. That’s what I saw in Science Left Behind, and also what I saw in the Little Black Book of Junk Science. Yes, not all of their contentions are the full story; for example, Agent Orange and DDT are dangerous, but not for the reasons that many (on the left!) claim they are. Organic food may represent one step towards more sustainable agricultural practices, but it’s also a flawed and limited scheme with what it can accomplish. (And yes, many of its effects are negative.)

There’s a lot to think about, and listening to someone who challenges the way you think has a lot to say for it. But I’m happy to share your thoughtful review; personally I agree with you about much of what’s in there, particularly about false equivalence.

Radiation dose chart. (Click to enlarge.) By XKCD, public domain.

From Anonymous Coward on the banana-radioactivity scale: “A single banana is slightly radioactive due to the presence of radioactive Potassium-40. As Sinisa Lazarek points out, an x-ray scanner’s intensity is around 0.1 µSv, which is roughly the same amount of radiation exposure as you would get from eating a single banana.”

Looks like I need to start eating bigger bananas if I want to take that trip to Iran!

The comet that gives rise to the Perseid meteor shower, Comet Swift-Tuttle, was photographed during its last pass into the inner Solar System in 1992. The influence of the gravity of the other planets has the potential to dramatically change its orbit, however. Image credit: NASA.

And finally, from Denier on cometary orbits: “The thing that amazes me is that an impact is possible at all. The solar system is 5 billions years old. Swift-Tuttle has had to make this loop hundreds of millions of times.”

This is actually a lot more fun than that; the data tells us the Swift-Tuttle is young as a comet! Remember when, a couple of years ago, we got the “Camelopardalids” for the first time? These gravitational interactions in the outer solar system (or the asteroid belt) happen relatively frequently, and comets don’t last long. Swift-Tuttle has likely been doing its dance for thousands of years, but probably not more than tens of thousands. And after the 4479 interaction, we can’t predict its motion well at all! That’s why it may get ejected, it may get hurled into the Sun, but it may (less likely, but still possible) collide with Earth. 1-in-a-million odds aren’t very high, but when you’re talking about human extinction, I’d be a lot happier with lower odds for sure!

If we get that long-term asteroid deflection program up and running, maybe giving Swift-Tuttle a nudge in the “get away from Earth” direction might not be the worst idea!

Thanks for a great week, folks, and see you back here for more science starting tomorrow!



from ScienceBlogs http://ift.tt/2vvf3sv

“Life is not a miracle. It is a natural phenomenon, and can be expected to appear whenever there is a planet whose conditions duplicate those of the Earth.” ―Harold Urey

It’s been yet another fascinating week of scientific stories here at Starts With A Bang! But as of the last 48 hours, there’s something I absolutely have to talk about: the “Unite The Right” hate rally in Virginia, accompanied by violence and murder. They say that in order for evil to triumph, all that you need is for good people to stand by and do nothing. When I was a kid — small, young, weak, inexperienced — I saw lots of people get beaten up, taken advantage of, mugged, robbed… and I didn’t do anything. Why? Because I was afraid for myself, for what would happen to me if I did. But I look at the world now, and I see it differently: what happens to us all if I don’t do anything? What happens if none of us stop this madness? It’s time to stand up alongside one another and demand equal treatment, legally, for everyone.

We live in a country where a black man will be criticized and even blacklisted from his job for taking a knee during the national anthem because he’s making a statement about equal rights and protections under the law, but the rights of neo-nazi murderers to hatch terrorism plots and violently attack counter-protesters (two pretty illegal things, by the way) are not even addressed by our country’s leadership. In 2017, more than 70 years after the world united to defeat fascism and white supremacy and oppression, actions like these are not condemned by the president. My grandfathers fought those Nazis, alongside the rest of the free world. It is up to every one of us — whether we’re white or persons of color; whether we’re men, women, or non-binary; whether we’re Christian or not; whether we’re cis or straight or citizens or not — to recognize that we’re all human beings, and that we have every right to demand those same human rights: life, liberty, and the pursuit of happiness. That is what America is about.

The (public domain) State Flag of Virginia. No joke.

Virginia, you have the most hateful state flag in the entire country. You changed it in 1861, after you seceded, to make it about murdering what you perceived as a tyrannical leader, in a Shakespearian scene. Four years later, theatre actor John Wilkes Booth did exactly this, acting out a scene from his favorite play in a way, murdering Lincoln the same way Brutus and Cassius murdered Caesar. Those three infamous words, sic semper tyrannis, are from Shakespeare, are emblazoned on the Virginia flag, and were shouted by Booth as he shot Lincoln in the head. We have a long heritage of hate, slavery, and murder in this country, and it is up to all of us to renounce rather than celebrate these awful parts of our nation’s past. We are moving forward, and no amount of hatred or demonization or violence is going to solve any of our nation’s problems. We will fight this hate with our words, with our bodies, and if necessary, with our lives. And in the end, just like always, hate will lose.

I had to say that. I cannot stand by and only talk about science when there are these other atrocities happening right here. It’s time to make a difference. It’s time to get involved. And it’s time to speak out. Nazis cannot make us afraid, and everyone needs to know that all of America is united against this hate. Even if the President is silent about it.

With that said, let’s get into the science. There’s been a lot to explore, question, and go over, despite all the things we disagree with one another on. Thankfully, there are scientific truths that, whether we agree with one another or not, are all true nonetheless. (And thank you to those who left positive comments over the last week. I came, I saw, I appreciated!) Here are the six stories we’ve told that have given you plenty to think about over the past week:

I’ll tell you all that there are at least three new podcasts coming out where I’m a guest — all related to Treknology, as far as I know — and for those of you who’ll be down at Brooks Winery in Salem next Sunday and Monday for the total solar eclipse, I’ll see you there! With all that said and done, let’s get right into our comments of the week!

32 images of the 2016 eclipse were combined in order to produce this composite, showcasing not only the corona and the plasma loops above the photosphere with stars in the background, but also with the Moon’s surface illuminated by Earthshine. Image credit: Don Sabers, Ron Royer, Miloslav Druckmuller.

From Michael Hutson on why eclipse science is still important: “Why is ground observation of total eclipses still so important when we have had manned and unmanned observation from orbit for decades?”

It’s absolutely true that we have space-based observation of the Sun and its corona; we’ve used radio astronomy to measure the shifting positions of stars over the course of a year; we’ve used gravitational lenses to better test and constrain relativity; and it’s things like stereographic satellite imagery and lunar laser ranging that have enabled us to determine the shape of the Moon’s shadow on Earth. Yes, the vast majority of scientifically useful eclipse data is historic, from validating relativity to measuring the coronal temperature and nature to the discovery of plasma loops to coronal mass ejections.

More than 2/3 of the American population is within a single day’s driving distance of the path of totality. This could create the worst traffic jam in American history. Image credit: Michael Zeller / greatamericaneclipse.com.

But there are still things we can do from the ground that have advantages, particularly the ones that are Earth-related. The uninterrupted land mass that this eclipse will pass over allows for the opportunity to understand atmospheric and temperature changes, the relationship between the Moon’s shadow and phenomena here on Earth’s surface, and the short-term but continuous variation in the Sun’s luminosity. Yes, we can do many things better from space, but we live here on Earth, and there’s still more science to be done!

A room where the walls, even if completely covered with mirrors, would never have every location illuminated, was a mathematically interesting conjecture that was only solved recently. Image credit: Mathematical Sciences Research Institute (MSRI) / Numberphile / Brady Haran / Howard Masur.

From dean on how certain problems in math have incremental progress made towards them: “More directly, a slightly simpler version may be attacked first, with interest as much on the process used to solve it as the solution. As restrictions on the problem statement are weakened work (often) goes to modifying what worked earlier in hopes on the more general problem.”

This is true, and is quite a precise and laudable statement. We do this in physics, too, except in physics we simplify deliberately. Think about what you’d need to know to successfully model a physical system accurately: the physical properties of all the particles in the Universe, relative to one another, their interrelationships and entanglements, and all the forces between them, as well as how it all evolves over time in a well-defined, relativistic and quantum context. Sounds like a tall order, doesn’t it?

The big strength of physics is its ability to simplify. The strength of physicists is in modeling: in knowing how to chew on the meat and throw away the bones of the problem. If you can boil down a problem to its key essence and solve that simplified version, that’s huge. If you could take the entire Universe and simulate all the physical interactions taking place, it would be interesting, too, but it would take a computer with the computing power of the entire Universe to do it, and it wouldn’t teach you anything new. Relating equations, theories, and models to physical phenomena is where it’s at.

The fabric of spacetime, illustrated, with ripples and deformations due to mass. A new theory must be more than identical to General Relativity; it must make novel, distinct predictions. Image credit: European Gravitational Observatory, Lionel BRET/EUROLIOS.

The fabric of spacetime, illustrated, with ripples and deformations due to mass. A new theory must be more than identical to General Relativity; it must make novel, distinct predictions. Image credit: European Gravitational Observatory, Lionel BRET/EUROLIOS.

From CFT on a perceived weakness in relativity: “…there is no known solution to even TWO masses (much less more than two) in the same space time matrix. That’s not a little thing to gloss over like a minor typo.”

Nope; it’s a testament to how complicated and intricate a theory like General Relativity is. But just because we can model a system that is too difficult to solve exactly (or analytically) doesn’t mean it’s any less valid. Reread that last sentence a few times; if you can absorb the information in it, you’ll understand why your argument for the “wrongness” of relativity (or the Navier-Stokes equation, or pretty much any complex physical system) holds no water.

Signs and protesters from the 2013 March Against Monsanto in Vancouver, BC. While there may be legitimate complaints over our modern agricultural system, GMOs are not the evil technology that people make them out to be. Image credit: Rosalee Yagihara of Wikimedia Commons.

From John on making a difference in science: “The subjective portion is deciding what parts of Science are “fringe”.”

This is true, and I fully admit that I have my own opinions on that matter. I am aware that although there are objective criteria in there, all of the ones I use are not (and cannot be, by their nature) objective. The danger comes when we present a subjective criterion as an objective one, and that’s something we’re all at risk for. I hope you enjoyed my review of the Little Black Book of Junk Science, whose authors have a right-wing bias, but that doesn’t make the science they present any less valid. It’s important to consider views that challenge our own, otherwise we’ll never learn anything new or be open to possibilities that are foreign to us.

In warm-weather years, which are statistically more likely with global warming, large, more powerful hurricanes, like 1985's Hurricane Elena, are more likely, but there will be fewer of them. Image credit: Image Science and Analysis Laboratory, NASA-Johnson Space Center.

In warm-weather years, which are statistically more likely with global warming, large, more powerful hurricanes, like 1985’s Hurricane Elena, are more likely, but there will be fewer of them. Image credit: Image Science and Analysis Laboratory, NASA-Johnson Space Center.

From Paul Dekous on Hurricane Elena: “Damn, I thought you were using that Hurricane Elena image on top of the page to answer how ‘Black Holes’ at the center of large galaxies could be voids.”

Nope, just to talk about hurricanes and other weather-based natural disasters. Black holes can’t really be “voids” in any meaningful sense, but the similarities between an “eye” of a storm and the cloud bands and an event horizon of a black hole and its accretion disk can be visualized in an analogous fashion. I’d say that’s fair!

The stars within and beyond the Pillars of Creation are revealed in the infrared. While Hubble extends its view out to 1.6 microns, more than twice the limit of visible light, James Webb will go out to 30 microns: nearly 20 times as far again. Image credit: NASA, ESA/Hubble and the Hubble Heritage Team.

From Brian K. Grimm on why we can’t all just get along: ” I do not understand the type of people that can look at a suite of scientific data, then pull specific corner cases from that data and say ‘all these hundreds of other analyses can’t be right, because of this one.’ I don’t just see it in physics either. I see it in finance/economics, politics, history, and religious discussions. Why is it so hard to agree on what reality is?”

I’m not a psychologist, and I don’t know that psychologists — even the ones that study bias and the Culture Wars — have the answer, so what you’re getting from me is a guess. My guess is that, for some people, particularly when it comes to some topics, getting a specific answer or reaching a specific conclusion is more important than those other things. If it’s part of your very identity that the world be flat, then your options are either to accept a round Earth and deny your core identity, or to hold onto your core identity and insist that the world is flat… and that’s when the logical and rhetorical gymnastics enter.

Some people love that game: the arguing and the argument-crafting, but I’m not one of them. I’d rather just earnestly ask after the truth, find the best answers we can arrive at, and share those results. Those of you who find your core identity in disagreement with my own (or what you perceive my own to be) will find an avenue to attack that too, but don’t worry. By this time next year, I’ll be 40, which, according to Mike Gundy, means I’ll be able to take the heat.

An artist’s impression of the three LISA spacecraft shows that the ripples in space generated by longer-period gravitational wave sources should provide an interesting new window on the Universe. LISA was scrapped by NASA years ago, and will now be built by the European Space Agency, with only partial, supporting contributions from NASA. Image credit: EADS Astrium.

From Michael Mooney on the ridiculousness of relativity: “I pointed out how totally ridiculous that claim is.”

Well, to someone who’s unwilling to accept the Universe as it is, the Universe is ridiculous. Electricity is ridiculous; gravitation is ridiculous; motion is ridiculous; and just wait until you get to quantum physics. It is not up to the Universe to bow to your claims of what makes sense and what doesn’t; the Universe does what it does and it’s up to us to decode how that works, and what predictions we can make in a variety of physical scenarios. Relativity has been doing that, correctly, for over 100 years. You are an onlooker, pointing and laughing, all the while reaping the benefits of relativity. Try using a GPS device (if you can find one) that doesn’t use relativity, and see how that works for you; you won’t like it.

Image credit: ESO / L. Calçada.

This artist’s impression shows the magnetar in the very rich and young star cluster Westerlund 1. Image credit: ESO / L. Calçada.

From eric on the “z” of a neutron star: “Unless that neutron star is in a *very* empty region of space, there will be a constant infallinng of particles. If the stuff falling in has protons (and it probably will), there will be some time required for those protons to be converted.”

Oh, you don’t need to go there! A neutron star only has about 90% of its mass in the form of neutrons; the outer 10% of its mass is more like a mix of protons, neutrons and even electrons. There ought to be atoms on a neutron star’s surface. Without those charged particles, you’d never be able to get a magnetic field in your neutron star, and yet they have the strongest magnetic fields in the Universe! The question, though, is whether it’s fair to consider the entire star as a single nucleus, or only a fraction of the core, and I think it’s the latter. But I am uncertain that the matter has been scientifically settled.

The increased emission of greenhouse gases, notably CO2, can have a massive impact on Earth’s climate in just a few hundred years. We’re witnessing that happen today. Image credit: U.S. National Parks Service.

From Another Commenter on a challenge to the climate consensus: “Herer’s (sic) an interesting news item about of reliable the data is from the signatories to Paris Climate Accord.
http://ift.tt/2uB7HzV

That is interesting. What it says, for those who won’t read it, is that a number of nations may be lying about what their actual emissions are versus their reported emissions. Veritas, my friends.

A remote camera captures a close-up view of a Space Shuttle Main Engine during a test firing at the John C. Stennis Space Center. Hydrogen is preferred as a fuel source in rockets due to its low molecular weight and the great abundance of oxygen in the atmosphere for it to react with. Image credit: NASA.

From Alan G. on calling out my rocket fuel caption: “The rocket engine photo caption is curious. Rocket engines don’t use atmospheric gaseous oxygen when running. They have to carry all of their own oxidizer with them also, along with their fuel.”

I’m impressed at how diligent you were to catch this! Yes, in principle, there’s a great abundance of oxygen in the atmosphere, and if you had O2 intake, you could react it with the hydrogen fuel inside.

But in practice, the act of taking in oxygen to react with the hydrogen will cost you more in terms of air resistance and the collisions of particles at those high relative speeds (plus your lack of ability to control the reaction rate as you went to low-oxygen elevations) means that it’s better to bring your oxygen liquid fuel with you, too. Well spotted, and thanks for coaxing me to go the extra mile!

A plume of smoke from wildfires burning rises over Fort McMurray in this aerial photograph taken in Alberta, Canada. The entire Pacific Northwest region of North America is suffering from severe wildfires, and the season hasn’t even peaked yet. Image credit: Darryl Dyck/Bloomberg.

From PJ on wildfires in Oregon: “Would need to get the good words of warning out to the general public and overseas travelers who may not be aware of the local conditions.”

Between the fires, the unpredictable winds, and cloud cover — including the haze cover from smoke in the copious Canada wildfires — a great many locations in the three westernmost states to see the 2017 eclipse will be at risk of having the Sun obscured during totality. Going to the coast may not solve the issue, either. Like over a million others, I’ll be rolling the dice a week from Monday!

Relic microbes revealed by a scanning electron microscope in the ALH84001 meteorite, which originated on Mars. It is unknown whether the microbes are of Martian origin or not. Image credit: NASA, 1996.

From jvj on wanting to be NASA’s planetary protection officer: “I’m perfect for the job. Have seen all the Star Trek TV shows & movies. I enjoy giving orders to menials. Our motto: “We come in Peace.” We can enslave any life forms we find & dig up all the diamonds & gold & drill for oil everywhere on each planet we take over.”

The great danger of contamination is a real one, and it may have already taken place naturally. Do you see this image above? That’s a fragment of a meteor that came from Mars, but it was found on Earth. When you get a massive impact from space on a rocky world — planet, asteroid, moon, or Kuiper belt object — it kicks up debris that can sometimes go back into space and travel to another world. If we find Mars rocks on Earth, does it not stand to reason that Earth rocks made their way to other worlds in the Solar System, too?

It’s worth thinking about, because despite our best efforts to decontaminate our spacecraft before we send them out exploring (and we may have failed at that with our earlier missions to Mars, for example), it may already be too late.

Correctly calibrated satellite data, as well as the more recent temperature data up through 2016, shows that climate predictions and observations are perfectly in line with one another. Image credit: HadCRUT4.5, Cowtan & Way, NASA GISTEMP, NOAA GlobalTemp, BEST, via Ed Hawkins at Climate Lab Book.

From Denier on a nice try: “First of all, you should at least be honest about what you are trying to do. You are trying to de-platform scientific evidence that fails your personal political litmus test. It has nothing to do with ‘good’ science. Santer (2017) is good science. Nature thinks so. You summarily dismissed it without reason. You simply didn’t like what it said. It didn’t support your political narrative so you wished it into the corn field.”

It is a nice try. I appreciate the thoughtfulness of the argument you made, because it’s a well-crafted narrative and it’s very compelling. And yes, I agree that Santer et al. (2017) is good science; Santer is one of the top scientists in the field of climate science. But, as always, what I’ve urged you to do in climate arguments is to be quantitative. Yes, the paper itself says that near-term, recent warming has been overestimated, elucidated why, and quantified by how much. It seems we’re in agreement there.

So tell me, then, how much has the warming been overestimated by the models? What percentage of the models overestimated the warming, before the Santer paper came out? (Hint: it’s less than the 95% that Heartland and UAH claimed, which is a claim that you defended, and which is data that you referenced, repeatedly, claimed was accurate, and never backed down from.) How well do the models do now that they have this improvement?

Yes, I didn’t address it, because it was a small contribution that has only mild relevance to a much larger story. You are crafting a narrative of “Ethan is dismissing evidence because he doesn’t like what it says” when in fact that is what I have witnessed not only you but literally everyone saying the same things as you doing for more than two decades now. (History tells me it may be longer than that, but I wasn’t really aware of the basic scientific story until the mid-1990s.) This is the Trump strategy — accuse your opponents of doing the exact thing you’re guilty of — and it worked for him. You add in the strategy of “focusing on the one factual detail where you are correct, exaggerate its importance, and try to derail the rest of the argument.”

Daffy Duck is smart enough to see what’s going on in a situation, but never figures out how to control what happens.

I feel like Daffy Duck in this situation. You know those old Warner Bros. cartoons with Bugs, Daffy, and Elmer Fudd? Elmer Fudd is not only unable to control the situation, but he’s unable to comprehend it, and always comes out on the losing side. Bugs understands the situation, and is able to manipulate the situation to his advantage; he controls it. Daffy is a tragicomic figure, though, who understands the situation but finds himself unable to control it, even though he sees how Bugs is manipulating it and hates the unfairness of it all. Who knows? You’re fighting your battle in the court of public opinion, and you’re a lawyer. Maybe it’ll work for you, too?

But irrespective of that, I will give you mad props for reading Gavin Schmidt and Ben Santer; their work is top notch. You and I may always disagree on policy, but if you’re reading their work, we may someday wind up agreeing on the facts.

This illustration of a black hole, surrounded by X-ray emitting gas, showcases one of the major ways black holes are identified and found. Based on recent research, there may be as many as 100 million black holes in the Milky Way galaxy alone. Image credit: ESA.

This illustration of a black hole, surrounded by X-ray emitting gas, showcases one of the major ways black holes are identified and found. Based on recent research, there may be as many as 100 million black holes in the Milky Way galaxy alone. Image credit: ESA.

From Omega Centauri on black holes in the Milky Way: “Those are remarkably large numbers. I would think the dwarf galaxies would resemble (in terms of metalicity and BH mass spectrum), the early larger galaxies. In the later category, have enough non-so-low metalicity stars formed to overwhelm the initial distribution?”

That’s part of what’s so exciting; dwarf galaxies aren’t similar to the Milky Way. Bigger galaxies have:

  • larger gas fractions (because the gas doesn’t get ejected during star formation),
  • more generations of stars (because of more major and minor mergers),
  • higher mass stars (because of more mass available, on average),
  • but higher metallicity (because of more generations and more mass),
  • so their high-mass stars shed more mass during their lives,

leading to smaller but far more numerous black holes. There are, if you’re curious, about ten times as many neutron stars as black holes in each galaxy.

Front cover of the hard copy of the Little Black Book of Junk Science. Image credit: American Council on Science and Health.

From Christopher Winter on Junk Science and ideology: “Having read Science Left Behind, of which Alex [Berezow] is co-author with Hank Campbell, I would be very reluctant to put credence in this book. The negative review on Amazon calls it “A pseudoscientific attempt to debunk pseudoscience.” That’s about what I’d expect.”

People with different ideologies than you will, in fact, take the same facts, the same data, and pick out different points to highlight that are still true. That’s what I saw in Science Left Behind, and also what I saw in the Little Black Book of Junk Science. Yes, not all of their contentions are the full story; for example, Agent Orange and DDT are dangerous, but not for the reasons that many (on the left!) claim they are. Organic food may represent one step towards more sustainable agricultural practices, but it’s also a flawed and limited scheme with what it can accomplish. (And yes, many of its effects are negative.)

There’s a lot to think about, and listening to someone who challenges the way you think has a lot to say for it. But I’m happy to share your thoughtful review; personally I agree with you about much of what’s in there, particularly about false equivalence.

Radiation dose chart. (Click to enlarge.) By XKCD, public domain.

From Anonymous Coward on the banana-radioactivity scale: “A single banana is slightly radioactive due to the presence of radioactive Potassium-40. As Sinisa Lazarek points out, an x-ray scanner’s intensity is around 0.1 µSv, which is roughly the same amount of radiation exposure as you would get from eating a single banana.”

Looks like I need to start eating bigger bananas if I want to take that trip to Iran!

The comet that gives rise to the Perseid meteor shower, Comet Swift-Tuttle, was photographed during its last pass into the inner Solar System in 1992. The influence of the gravity of the other planets has the potential to dramatically change its orbit, however. Image credit: NASA.

And finally, from Denier on cometary orbits: “The thing that amazes me is that an impact is possible at all. The solar system is 5 billions years old. Swift-Tuttle has had to make this loop hundreds of millions of times.”

This is actually a lot more fun than that; the data tells us the Swift-Tuttle is young as a comet! Remember when, a couple of years ago, we got the “Camelopardalids” for the first time? These gravitational interactions in the outer solar system (or the asteroid belt) happen relatively frequently, and comets don’t last long. Swift-Tuttle has likely been doing its dance for thousands of years, but probably not more than tens of thousands. And after the 4479 interaction, we can’t predict its motion well at all! That’s why it may get ejected, it may get hurled into the Sun, but it may (less likely, but still possible) collide with Earth. 1-in-a-million odds aren’t very high, but when you’re talking about human extinction, I’d be a lot happier with lower odds for sure!

If we get that long-term asteroid deflection program up and running, maybe giving Swift-Tuttle a nudge in the “get away from Earth” direction might not be the worst idea!

Thanks for a great week, folks, and see you back here for more science starting tomorrow!



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Kid Art Update [Uncertain Principles]

Our big home renovation has added a level of chaos to everything that’s gotten in the way of my doing more regular cute-kid updates. And even more routine tasks, like photographing the giant pile of kid art that we had to move out of the dining room. Clearing stuff up for the next big stage of the renovation– cabinets arrive tomorrow– led me to this stuff, though, so I finally took pictures of a whole bunch of good stuff. (On the spiffy new tile floor in the kitchen, because the light was good there…)

The kids’s school sends home portfolios of what they’ve done in art class for the year, and I collected those photos together into a Google Photos album for easy sharing, because they’re pretty cool. My favorite piece of the lot is this polar bear by SteelyKid:

Polar bear by SteelyKid.

That’s in pastel chalk on construction paper; you can see some preliminary sketches of the bear in the album. She drew the scene in pencil, colored it in chalk, then traced important lines with a marker. It’s very cool.

The Pip has some neat stuff in his portfolio, too– I especially like that they had the kids making Mondrians out of strips of construction paper– but my favorite of his was a non-art-class drawing that was in the pile:

The Pigeon, by The Pip.

That’s a very credible rendering of Mo Willems’s Pigeon for a kindergartener…

Anyway, other than that, life continues in the usual whirl. I’m getting really tired of living out of a mini-fridge in the living room and a temporary sink in the kitchen that’s at about knee level to me (when I have to wash dishes, I pull up a chair and sit down, which takes the stress on my back from “agonizing” down to “annoying”). But, cabinets this week, so we can see the oncoming train at the end of this tunnel…



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Our big home renovation has added a level of chaos to everything that’s gotten in the way of my doing more regular cute-kid updates. And even more routine tasks, like photographing the giant pile of kid art that we had to move out of the dining room. Clearing stuff up for the next big stage of the renovation– cabinets arrive tomorrow– led me to this stuff, though, so I finally took pictures of a whole bunch of good stuff. (On the spiffy new tile floor in the kitchen, because the light was good there…)

The kids’s school sends home portfolios of what they’ve done in art class for the year, and I collected those photos together into a Google Photos album for easy sharing, because they’re pretty cool. My favorite piece of the lot is this polar bear by SteelyKid:

Polar bear by SteelyKid.

That’s in pastel chalk on construction paper; you can see some preliminary sketches of the bear in the album. She drew the scene in pencil, colored it in chalk, then traced important lines with a marker. It’s very cool.

The Pip has some neat stuff in his portfolio, too– I especially like that they had the kids making Mondrians out of strips of construction paper– but my favorite of his was a non-art-class drawing that was in the pile:

The Pigeon, by The Pip.

That’s a very credible rendering of Mo Willems’s Pigeon for a kindergartener…

Anyway, other than that, life continues in the usual whirl. I’m getting really tired of living out of a mini-fridge in the living room and a temporary sink in the kitchen that’s at about knee level to me (when I have to wash dishes, I pull up a chair and sit down, which takes the stress on my back from “agonizing” down to “annoying”). But, cabinets this week, so we can see the oncoming train at the end of this tunnel…



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Damore’s Pseudoscientific Google manifesto is a better evidence for sexism than it is for intellectual sex differences [denialism blog]

Pseudoscience is effective. If it weren’t, people wouldn’t generate so much of it to try to justify opinions not supported by the bulk of the evidence. It’s effective because people trust science as a method of understanding the world, and ideological actors want that trust conferred to their opinions. They want their opinions to carry that authority, so they imitate science to try to steal some of that legitimacy for themselves. However, science is not flattered by this behavior, it is undermined and diminished.

The Damore Manifesto (PDF with hyperlinks) or “Google anti-diversity memo” is just such an example of pseudoscience, and largely by accident, it has gained outsize attention for what is essentially a C-grade highschool research paper. It has proven itself compelling, however, to a large number of people in the media, including intellectual lightweight David Brooks, who finds it so compelling he “>calls on Google’s CEO to resign. He makes the astonishing claim that Damore is championing “scientific research” while his opponents are merely concerned with “Gender equality” (Classic false bifurcation fallacy). He also declares Evolutionary Psychology to be “winning the debate” and goes on to talk about superior female “brain connectivity”, and with a sigh, I wonder what Snapple cap he learned these “facts” from. Not only is this highly debatable, but even if male vs female patterning exists there is no reason to think that it is unaffected by environment and cultural patterning on brain plasticity. If boys supposedly have more developed motor cortex and girls more emotional wiring is that because the boy’s first toy was a ball, and the girl’s is a doll? The declarations that this is a settled question is absurd. We don’t know, and there are too many confounders to be making statements about biological inevitability with regards to gender when we are positively soaking in gendered norms of behavior.

XKCD evo-psych

Brooks conclusion, in an example of being incompetent and unaware of it, is the Google leadership either “is unprepared to understand the research (unlikely), is not capable of handling complex data flows (a bad trait in a C.E.O.) or was simply too afraid to stand up to a mob”. He never considers the possibility, and given this is Brooks the inevitability, that he is wrong and has been hoodwinked by rather mediocre pseudoscientific argumentation. In these reactions, we learn more about these authors’ biases than we have learned about the suitability of women to write code, as the “manifesto” conforms to Brooks’ rather predictable biases and therefore receives almost no skepticism relative to the weight of the claims, which are hefty. Why is Brooks so blind to the shoddy scholarship of the Google memo?

Ironically, within the memo itself, we have the answer:

We all have biases and use motivated reasoning to dismiss ideas that run counter to our internal values.

With this we see the continuing evolution of pseudoscience, as they continue to evolve and mimic actual scientific debate and knowledge, the scientific language of motivated reasoning (the cultural or identity-protective cognition responsible for denialism), has filtered into their lingo. This is fascinating in itself, as the author has clearly read about motivated reasoning, yet is completely blind to it for the rest of his essay. This essay is classic pseudoscience, built on motivated reasoning, that uses a half a dozen references, cherry-picked from the literature, to make the astonishing claim that women are underrepresented in his white-collar workforce because of fundamental biological differences (read defects) affecting their capability to perform in a purely intellectual job. It is another in a long line of “just so” pseudoscientific justifications of gender or racial disparities that just happens to defend the status quo (subtext – “why I shouldn’t have to sit through any more mandatory diversity training”).

This is a wonderful example of Panglossian reasoning and if you haven’t read Candide, here is an example:

Master Pangloss taught the metaphysico-theologo-cosmolonigology. He could prove to admiration that there is no effect without a cause; and, that in this best of all possible worlds, the Baron’s castle was the most magnificent of all castles, and My Lady the best of all possible baronesses.

“It is demonstrable,” said he, “that things cannot be otherwise than as they are; for as all things have been created for some end, they must necessarily be created for the best end. Observe, for instance, the nose is formed for spectacles, therefore we wear spectacles. The legs are visibly designed for stockings, accordingly we wear stockings. Stones were made to be hewn and to construct castles, therefore My Lord has a magnificent castle; for the greatest baron in the province ought to be the best lodged. Swine were intended to be eaten, therefore we eat pork all the year round: and they, who assert that everything is right, do not express themselves correctly; they should say that everything is best.”

Candide listened attentively and believed implicitly, for he thought Miss Cunegund excessively handsome, though he never had the courage to tell her so. He concluded that next to the happiness of being Baron of Thunder-ten-tronckh, the next was that of being Miss Cunegund, the next that of seeing her every day, and the last that of hearing the doctrine of Master Pangloss, the greatest philosopher of the whole province, and consequently of the whole world.

Everything old is new again. What Voltaire was mocking were the glib and facile justifications of injustice in his time, which presume the current state of the world is in its best possible state and everything you see is the result of natural inevitability. Candide in Silicon Valley would exclaim, “Oh Pangloss, why is it that men are so over-represented in tech?” and Pangloss’s response, “For men are better at tech because of their intrinsic personality traits, and in this best of all possible worlds, male personality traits and even their flaws make for the best-possible technology and business practices.”

Anyone who has been following the Uber saga might question Panglossian reasoning about why tech is male. Even if the tech sector, as it exists today, is male-dominated because men perform better in the current pathological and Machiavellian environment, that doesn’t mean this is ideal, that it isn’t hugely, culturally flawed, and maybe desperately in need of womanly empathy. Taking such data at face value, an industry that is blind to the needs of fully half of its customers, or blind to the potential benefit of the perspective of the other half of the population, is playing with fire. Do we really think situations like Uber’s are a coincidence given the toxic masculinity of its leadership? The male-dominated model is not the best of all possible worlds. The male-dominated model was built by men, for men, so why be surprised when less women are attracted to it and fare worse within it.

Other authors have already done some of the heavy lifting, tackling the low scientific credibility of these claims and placing them in the historical context of the usual power-dynamic of trying to scientifically justify the status quo. These are useful, but we can expand upon them and use this essay as a learning opportunity for how to detect pseudoscience, so one hopefully doesn’t have to go through all the effort of endless debunking every time an ideologue vomits up some new dreck to explain why it’s only natural males, or whites, or whomever comes out on top.

And that is one thing we should immediately detect, the similarity to historical “just-so” arguments of scientific racism from the last few centuries. These arguments are old news, as anyone who has read Stephen Jay Gould’s Mismeasure of Man can tell you, and crop up whenever the dominant class in society has to explain why they’re on top without admitting it’s because they pushed everyone else down then pulled the ladder up after themselves. Once you hear people talking about why current race or gender divisions are natural, one should immediately take whatever argument is coming with a massive dose of skepticism. We have heard this nonsense before.

Let’s start with Damore’s words so it’s clear I’m addressing the scientific claims of his argument, contained in the last element of his TL;DR section and supported by the handful of actual scientific citation.

Differences in distributions of traits between men and women may in part explain why we don’t have 50% representation of women in tech and leadership. Discrimination to reach equal representation is unfair, divisive, and bad for business.

Now keep in mind, this is in the context of an 69:31 M:F ratio at Google which is even higher in the engineering at 80:20

Possible non-bias causes of the gender gap in tech
On average, men and women biologically differ in many ways. These differences aren’t just
socially constructed because:
● They’re universal across human cultures
● They often have clear biological causes and links to prenatal testosterone
● Biological males that were castrated at birth and raised as females often still identify
and act like males
● The underlying traits are highly heritable
● They’re exactly what we would predict from an evolutionary psychology perspective

Note, I’m not saying that all men differ from all women in the following ways or that these
differences are “just.” I’m simply stating that the distribution of preferences and abilities of men
and women differ in part due to biological causes and that these differences may explain why
we don’t see equal representation of women in tech and leadership. Many of these differences
are small and there’s significant overlap between men and women, so you can’t say anything
about an individual given these population level distributions.

It’s so nice that he cleared that up about not applying these findings to individuals this is hard to reconcile with the fact he is suggesting the 69:31 ratio or 80:20 engineering ratio at Google is in some meaningful way affected by these differences. Further, each of these statements lacks citation and can not be taken at face value, and I would describe them as either all wrong or grossly oversimplified. While the differences in gendered personality he subsequently describes is consistent within any culture examined, they are not consistent between cultures, which shows these are still culturally-dependent and not purely biologically deterministic (And of course, there is no matriarchal culture for comparison 😉 ) I have no idea why he conflated the research on androgens on personality development using CAH or androgen insensitivity with studies of personality changes in castration related to sex-reassignment, and prostate cancer treatment (if anyone can find a study of those “castrated at birth” please show me as I cant find it – I suspect he’s confused). He mixes two effects by saying androgens in the womb have effects on subsequent personality (likely but difficult to separate from gender norms) but then saying traits are heritable. Which is it? The Y chromosome or exposure to androgens? One is genetic, one is congenital. Finally, it’s rare to find examples where EP is truly “predicting” anything and not just indulging in the just-so stories and adaptationism (my favorite example of an evo-psych just so), i.e. more Panglossian logic. The field is…problematic, and strong statements about EP predictions like “exactly what we would predict from an evolutionary psychology perspective” should set off alarm bells.

Each of these statements are gross simplifications of large bodies of research, some of which are highly problematic areas with reproducibility problems, to justify a 2:1 or even 4:1 difference in hiring of men:women at Google. There is a general rule that “extraordinary claims require extraordinary proof”, well here is a man saying the reason Google has 2-4x as many men as women isn’t just the known, historic, institutional sexism that kept women from voting, owning property, having access to college education, equal pay etc., but fundamental biological differences across all cultures, that exists from birth, programmed by testosterone yet highly heritable (wah?) and conforming to predictions of a controversial scientific field that starts with conclusions and works backward to explanation. These effects are large enough, apparently, that Google should not try for parity in hiring and stop diversity training. Riiight. You better have some rock solid data to back this up.

Let’s look at the extraordinary data on why the women are so terribly disadvantaged based on their biology for software engineering (heads up, it’s a couple of wikipedia articles, and :

Personality differences
Women, on average, have more:

Openness directed towards feelings and aesthetics rather than ideas. Women generally also have a stronger interest in people rather than things, relative to men (also interpreted as empathizing vs. systemizing).
These two differences in part explain why women relatively prefer jobs in social or artistic areas. More men may like coding because it requires systemizing and even within SWEs, comparatively more women work on front end, which deals with both people and aesthetics.
Extraversion expressed as gregariousness rather than assertiveness. Also, higher agreeableness.
This leads to women generally having a harder time negotiating salary, asking for raises, speaking up, and leading. Note that these are just average differences and there’s overlap between men and women, but this is seen solely as a women’s issue. This leads to exclusory programs like Stretch and swaths of men without support.
Neuroticism (higher anxiety, lower stress tolerance).This may contribute to the higher levels of anxiety women report on Googlegeist and to the lower number of women in high stress jobs.
Note that contrary to what a social constructionist would argue, research suggests that “greater nation-level gender equality leads to psychological dissimilarity in men’s and women’s personality traits.” Because as “society becomes more prosperous and more egalitarian, innate dispositional differences between men and women have more space to develop and the gap that exists between men and women in their personality becomes wider.” We need to stop assuming that gender gaps imply sexism.

For this segment he cites the wikipedia page on “sex differences in psychology; personality traits”, only useful for some background, not proof women!=engineers.

He cites This paper, which summarizes meta-analyses in the literature of personality with a reproducible effect showing that in a 6 dimensional model of personality traits women and men consistently score differently on being interested in “persons” vs “things”, and also that these sex differences in behavior are consistent across cultures. To be fair supporting literature exists which correlates these personality trends with differences in vocational choices, so it’s plausible that, all things being equal, there may be a gender gap in some professions based on personality traits.

This may be the only item of interest in his entire paper, as it is reproducible and there is evidence it impacts what choices the different sexes make about jobs. The problem I have with it is there is no way to control for the effect of how humans, starting when we’re toddlers, start to consolidate gender roles. If the image of the engineer or tech industry is predominantly male, this becomes a self-fulfilling prophecy. It also assumes that the current male-dominated status of tech couldn’t benefit from traits on the female axis including better interest in “persons” and creativity/artistic expression. The argument becomes a tautology, men are attracted to the tech sector because the tech sector is male. Add to that the tendency of institutions to maintain homogeneity by effects like in-group bias, and you see why male-dominated fields may remain static. Just imagine if we had accepted similar Panglossian logic 50 years ago that these gender-distributions as some kind of inevitable consequence of natural gender preferences, we’d still have only male doctors, lawyers, and executives, because, this is the best of all possible worlds, and there must be some evolutionary psychology to explain why there are no women doctors, or lawyers, or executives.

Damore then cites the wikipedia article on the Empathizing–systemizing theory. This appears to be moderately central to his argument, but again it is weak evidence. Not to beat a dead horse, but we are once again starting with the assumption that the current state of affairs represents some kind of ideal – the dominance of men in the field is “just so” because they’re more adapted to it, rather than they adapted the field to themselves or that there’s a host of historical factors such as women only got the right to vote in the last 100 years, co-ed schools in the last 50 years, they are still treated as second-class citizens including when it comes to pay. It also accepts one of the authors underlying assumptions, which is outside of my experience, which is that empathy is bad for engineering at Google. I can’t debate that, but least one former Googler has responded to this assertion and says absolutely not:

What I am is an engineer, and I was rather surprised that anyone has managed to make it this far without understanding some very basic points about what the job is. The manifesto talks about making “software engineering more people-oriented with pair programming and more collaboration” but that this is fundamentally limited by “how people-oriented certain roles and Google can be;” and even more surprisingly, it has an entire section titled “de-emphasize empathy,” as one of the proposed solutions.

People who haven’t done engineering, or people who have done just the basics, sometimes think that what engineering looks like is sitting at your computer and hyper-optimizing an inner loop, or cleaning up a class API. We’ve all done this kind of thing, and for many of us (including me) it’s tremendous fun. And when you’re at the novice stages of engineering, this is the large bulk of your work: something straightforward and bounded which can be done right or wrong, and where you can hone your basic skills.

But it’s not a coincidence that job titles at Google switch from numbers to words at a certain point. That’s precisely the point at which you have, in a way, completed your first apprenticeship: you can operate independently without close supervision. And this is the point where you start doing real engineering.

And once you’ve understood the system, and worked out what has to be built, do you retreat to a cave and start writing code? If you’re a hobbyist, yes. If you’re a professional, especially one working on systems that can use terms like “planet-scale” and “carrier-class” without the slightest exaggeration, then you’ll quickly find that the large bulk of your job is about coordinating and cooperating with other groups.

Essentially, engineering is all about cooperation, collaboration, and empathy for both your colleagues and your customers. If someone told you that engineering was a field where you could get away with not dealing with people or feelings, then I’m very sorry to tell you that you have been lied to. Solitary work is something that only happens at the most junior levels, and even then it’s only possible because someone senior to you — most likely your manager — has been putting in long hours to build up the social structures in your group that let you focus on code.

All of these traits which the manifesto described as “female” are the core traits which make someone successful at engineering. Anyone can learn how to write code; hell, by the time someone reaches L7 or so, it’s expected that they have an essentially complete mastery of technique. The truly hard parts about this job are knowing which code to write, building the clear plan of what has to be done in order to achieve which goal, and building the consensus required to make that happen.

Tom Smykowski says, engineers need more empathy

If true, this kind of knocks the teeth out of this particular “just so” justification that empathy is maladaptive. Is it possible, that the current culture of masculinity and therefore insularity is holding tech back? Couldn’t one make just as good an argument here, that Google hasn’t maxed its potential until it harnesses women’s superior social and interpersonal skills to help with things like teamwork and management? Is there no positive side to hiring women? And that is assuming these are large enough difference between women and men on these behavioral traits to justify hiring twice as many men as women.

Take a look at a recent paper from the theorist behind the E-S scale – Simon Baron-Cohen – and the differences on his Autism Spectrum Quotient scores (a newer scale Baron-Cohen has validated from the EQ SQ research and seems to have moved onto) for women vs men and STEM fields vs others that Damore is alluding to (I have to make some leaps here, Damore links the “E-S scale” wikipedia, which is a touch dated, without indicating a specific study, and ostensibly is referring to this work by Baron-Cohen who has advanced the idea of the “male mind” and autism being an excess of male mental traits – this itself has been critiqued as “neurosexist”). Studying an enormous database Baron Cohen finds a statistically-significant difference in AQ score between men and women, and women and those in STEM:

http://ift.tt/2uzSKmy

While this may be statistically significant, it’s still a tiny difference overall a matter of about 3 points on this scale by most measures I’ve read, and indeed STEM workers trend towards a similar 2-3 point higher AQ score. It is also hard to conclude the differences between women’s score and STEM is due to intrinsic or cultural factors – again, the best of all possible worlds fallacy, and it is no evidence to believe that 2-3 points difference in the mean score explains 2-4 fold gaps in hiring of men vs women. Draw a line at about 21 and ballpark an SD, of +/- 8 points, are there 2-4x as many men under the curve right there? Of course not. There’s too much meat under that curve to justify more than a couple of points difference. Alternatively, you could make an argument from the tails, that you could conceive of the extremes of the population such as AQ > 40 having approximately 2x as many men with this trait. One would have to believe that the population at google is so far shifted to the right in terms of male braininess, that the majority of the population at google has a mean AQ beyond 30 or 40. Is this the case? Unlikely, as the nonclinical range of AQ is consistently in the teens to twenties and those diagnosed with autistic spectrum disorder tend to score in the mid 30s.

At the same time that Damore is critical of reducing populations to their means when there is significant overlap, to believe his argument – that tech is segregated by gender because not enough women have the “male mind” described by Baron-Cohen – requires one to believe that the status-quo ratio represents the ideal workforce, that these tiny differences in gender behavior are so debilitating as to explain the 2-4x difference in hiring, and that nothing beneficial is brought to the table by “empathic” team members. This makes no sense, these differences are slight. The area under the curve doesn’t support that these tiny differences – even if they were intensely meaningful, could generate such large differences in hiring. The areas where the variance between the populations becomes larger than the female population size is far above typical scores for ASD. Is the contention that the neurotypical can’t code?

Barely worth mentioning, he alludes to negative female personality traits by including a link to this wikipedia article on Neuroticism. This is a similarly weak argument. Again the effect is meaningless in size, if you go to the primary literature it’s consistent but small. There is no evidence such an mild difference in gender behaviors with regards to neuroticism would result in such a dramatic difference in hiring or performance, nor is it explained why neuroticism would be less adaptive in engineering vs other fields.

Finally he cites this opinion piece dismissing wage gaps between genders from a Libertarian online magazine, ignored without comment.

Does anyone maybe feel already the evidence here is a bit…light? You’re going to tell an entire gender they can’t do engineering based on a 3 psychology papers showing small and likely irrelevant differences in gendered behavior, a couple of wikipedia pages, and a libertarian opinion piece about how the wage gap is imaginary? You are surprised when women read this and they’re pissed? Do those saying this is “science” like David Brooks want to maybe rethink their expertise on this topic? Because they’re not looking too competent right now. This is classic pseudoscience, a weak, cherry-picked literature is flogged to support some ideological nonsense.

Next Damore asks why might men be more suited for software engineering? Well he’s got a whole paragraph and three more “sciencey” citations to justify that:

Men’s higher drive for status
We always ask why we don’t see women in top leadership positions, but we never ask why we
see so many men in these jobs. These positions often require long, stressful hours that may not
be worth it if you want a balanced and fulfilling life.
Status is the primary metric that men are judged on4, pushing many men into these higher
paying, less satisfying jobs for the status that they entail. Note, the same forces that lead men
into high pay/high stress jobs in tech and leadership cause men to take undesirable and
dangerous jobs like coal mining, garbage collection, and firefighting, and suffer 93% of
work-related deaths.

To justify this he cites the Atlantic opinion piece “The War Against Boys” which counter-intuitively suggests women are better at school than boys, and it’s boys whose performance is undermined (and this helps Damore’s argument how?). He cites this paper on gender differences in mate selection criteria, sadly is paywalled but it’s conclusions are college men prefer good looks, and college women want financial success in a mate, therefore men are more competitive for status jobs in order to satisfy female sexual selection. One could point out, this is a gross simplification of human mating dynamics and is one effect among many in human attraction or every woman alive would coo over Donald Trump. Finally he cites this paper on effects of testosterone on college age men that found when injected with additional testosterone in an Ultimatum game they behaved more aggressively, but also more generous to those who made them bigger offers thus supporting the idea testosterone enhances “status seeking” behavior. Again one would have to believe this is a large enough effect that women and men have no interest in tech or engineering for any other reason than mate selection. Or show that those engineers seeking status are running higher testosterone levels than men in other “high status” jobs to show this is anything other than a suggestive result. It is further discredited by the fact that over the last 40 years women have pursued more and more “high status” jobs. Although their numbers are more uneven with regards to “things important” type (read engineering) fields, to say this is biological determinism and not male obstructionism is not justified based on a single testosterone experiment done in college students and a oversimplified view of mate selection. It ignores that women are perfectly capable of being engineers and functioning at the top of fields like physics or mathematics, and human mating behaviors are far more complex than “women are gold-diggers.”

Again. Does anyone here find the evidence here a bit light? David Schmitt seems to agree and his research is that being cited by Damore:

Still, it is not clear to me how such sex differences are relevant to the Google workplace. And even if sex differences in negative emotionality were relevant to occupational performance at Google (e.g., not being able to handle stressful assignments), the size of these negative emotion sex differences is not very large (typically, ranging between “small” to “moderate” in statistical effect size terminology; accounting for perhaps 10% of the variance1). Using someone’s biological sex to essentialize an entire group of people’s personality is like surgically operating with an axe. Not precise enough to do much good, probably will cause a lot of harm. Moreover, men are more emotional than women in certain ways, too. Sex differences in emotion depend on the type of emotion, how it is measured, where it is expressed, when it is expressed, and lots of other contextual factors. How this all fits into the Google workplace is unclear to me. But perhaps it does.

As to sex differences in mate preferences and status-seeking, these topics also have been heavily researched across cultures (for a review, see here). Again, though, most of these sex differences are moderate in size and in my view are unlikely to be all that relevant to the Google workplace (accounting for, perhaps, a few percentage points of the variability between men’s and women’s performance outcomes).

Culturally universal sex differences in personal values and certain cognitive abilities are a bit larger in size (see here), and sex differences in occupational interests are quite large2. It seems likely these culturally universal and biologically-linked sex differences play some role in the gendered hiring patterns of Google employees. For instance, in 2013, 18% of bachelor’s degrees in computing were earned by women, and about 20% of Google technological jobs are currently held by women. Whatever affirmative action procedures Google is using appear to be working pretty well (at least at the tech job level). Still, I think it’s important to keep in mind that most psychological sex differences are only small to moderate in size, and rather than grouping men and women into dichotomous groups, I think sex and sex differences are best thought of scientifically as multidimensional dials, anyway (see here).

Not exactly a ringing endorsement of Damore’s use of his research and the data on increasing “status” vs “things” jobs suggests women might have been settling for those jobs only as they were in enforced gendered roles. Schmitt also seems to agree, extraordinary claims require extraordinary evidence, and these effects are small. Linking gendered behavioral differences to massive differences in performance in tech or engineering is an enormous stretch of logic. Schmitt emphasizes uncertainty, and the need to recognize complex role of gender on human behavior, he sure sounds like a scientist (for an Evolutionary Psychologist 😉 ).

The one who doesn’t sound like a scientist is Damore, who it turns out falsely claimed to have a PhD, gave his first interviews to alt-right youtubers, compared Google to Soviet prison labor camps even wearing a “Goolag” shirt for his WSJ editorial. He sounds less like a scientist, and more like he’s read the Crank Howto. I don’t understand how he ever expected to keep his job, after it turns out he did not have a PhD, he blasted a crank manifesto at his workplace that demeans a significant portion of the Google workforce, managed to embarrass his company on a national level, and ultimately demonstrated fundamental incompetencies in analysis and workplace etiquette. He would probably benefit from some training along the empathy axis, but instead is nursing a google-sized persecution complex.

To summarize, a junior, not-PhD employee of Google has written a 10 page document which purports to explain that the massive imbalance in male:female ratio at the company is not necessarily due to historic struggles of women for equal representation in equality, readily measurable bias, or structural sexism, but is instead due to female biology. The evidentiary basis for this argument is 3 bullet points followed by 3 short paragraphs that cite a few wikipedia pages, some libertarian/rightwing opinion pieces, a handful of papers on gendered differences in behavior showing some interesting but small differences between men and women, a bizarre reference to data from males castrated at birth (please someone find me that paper), some handwaving about male/female sex selection and “status” belied by a 40 year trend in women increasingly taking higher status jobs, and a borderline sexist psychological theory about “masculine brains” with similarly small differences between men and women. Notably, all of his arguments are dependent on the assumption that the male brain is fundamentally better at engineering because they got these jobs first and are thus appropriately over represented, and qualities like empathy and interpersonal skills don’t contribute to what is already a flawlessly healthy corporate culture in tech. By this logic women don’t do well in this culture because female cognition is inadequate to the task, not because it’s hard to fit in as a woman in at the boys club.

http://ift.tt/2uzKWkN

He does not discuss or cite any of the extensive literature for the constant measurable bias women undergo in the workplace. His argument dismisses the more probable negative effects of historical oppression of women (denial of the vote, of property, of jobs, of education) well into the last century as well as ongoing structural sexism. He fails to link these effects to actual performance or interest in software engineering, he grossly oversimplifies the relationship between culture and behavior in favor of radical biological determinism, and wraps it into a typical Panglossian “just-so” story.

After predictably being fired for sending a crudely-argued, c-grade essay on why “girls like talking not math”, he has now made the rounds of the alt-right internet, the antediluvian editorial page of the WSJ, and has cried persecution at Google comparing himself to a slave laborer. He denies he’s an ideologue, even though as example of left wing denialism he cites John Tierney of the Manhattan Institute, and his argument that global warming scientists are the real threat to science (plus Rachel Carson DDT revisionism – yay!). By their fruits you shall know them.

What this shows is, the people who are impressed by his line of argumentation and series of events are ideologically-primed to accept it, not that they are particularly good judges of science. Pay attention to who buys into this uncritically, it’s better evidence for weak, sexist minds than it is for weak minds of a sex.



from ScienceBlogs http://ift.tt/2fCVU2a

Pseudoscience is effective. If it weren’t, people wouldn’t generate so much of it to try to justify opinions not supported by the bulk of the evidence. It’s effective because people trust science as a method of understanding the world, and ideological actors want that trust conferred to their opinions. They want their opinions to carry that authority, so they imitate science to try to steal some of that legitimacy for themselves. However, science is not flattered by this behavior, it is undermined and diminished.

The Damore Manifesto (PDF with hyperlinks) or “Google anti-diversity memo” is just such an example of pseudoscience, and largely by accident, it has gained outsize attention for what is essentially a C-grade highschool research paper. It has proven itself compelling, however, to a large number of people in the media, including intellectual lightweight David Brooks, who finds it so compelling he “>calls on Google’s CEO to resign. He makes the astonishing claim that Damore is championing “scientific research” while his opponents are merely concerned with “Gender equality” (Classic false bifurcation fallacy). He also declares Evolutionary Psychology to be “winning the debate” and goes on to talk about superior female “brain connectivity”, and with a sigh, I wonder what Snapple cap he learned these “facts” from. Not only is this highly debatable, but even if male vs female patterning exists there is no reason to think that it is unaffected by environment and cultural patterning on brain plasticity. If boys supposedly have more developed motor cortex and girls more emotional wiring is that because the boy’s first toy was a ball, and the girl’s is a doll? The declarations that this is a settled question is absurd. We don’t know, and there are too many confounders to be making statements about biological inevitability with regards to gender when we are positively soaking in gendered norms of behavior.

XKCD evo-psych

Brooks conclusion, in an example of being incompetent and unaware of it, is the Google leadership either “is unprepared to understand the research (unlikely), is not capable of handling complex data flows (a bad trait in a C.E.O.) or was simply too afraid to stand up to a mob”. He never considers the possibility, and given this is Brooks the inevitability, that he is wrong and has been hoodwinked by rather mediocre pseudoscientific argumentation. In these reactions, we learn more about these authors’ biases than we have learned about the suitability of women to write code, as the “manifesto” conforms to Brooks’ rather predictable biases and therefore receives almost no skepticism relative to the weight of the claims, which are hefty. Why is Brooks so blind to the shoddy scholarship of the Google memo?

Ironically, within the memo itself, we have the answer:

We all have biases and use motivated reasoning to dismiss ideas that run counter to our internal values.

With this we see the continuing evolution of pseudoscience, as they continue to evolve and mimic actual scientific debate and knowledge, the scientific language of motivated reasoning (the cultural or identity-protective cognition responsible for denialism), has filtered into their lingo. This is fascinating in itself, as the author has clearly read about motivated reasoning, yet is completely blind to it for the rest of his essay. This essay is classic pseudoscience, built on motivated reasoning, that uses a half a dozen references, cherry-picked from the literature, to make the astonishing claim that women are underrepresented in his white-collar workforce because of fundamental biological differences (read defects) affecting their capability to perform in a purely intellectual job. It is another in a long line of “just so” pseudoscientific justifications of gender or racial disparities that just happens to defend the status quo (subtext – “why I shouldn’t have to sit through any more mandatory diversity training”).

This is a wonderful example of Panglossian reasoning and if you haven’t read Candide, here is an example:

Master Pangloss taught the metaphysico-theologo-cosmolonigology. He could prove to admiration that there is no effect without a cause; and, that in this best of all possible worlds, the Baron’s castle was the most magnificent of all castles, and My Lady the best of all possible baronesses.

“It is demonstrable,” said he, “that things cannot be otherwise than as they are; for as all things have been created for some end, they must necessarily be created for the best end. Observe, for instance, the nose is formed for spectacles, therefore we wear spectacles. The legs are visibly designed for stockings, accordingly we wear stockings. Stones were made to be hewn and to construct castles, therefore My Lord has a magnificent castle; for the greatest baron in the province ought to be the best lodged. Swine were intended to be eaten, therefore we eat pork all the year round: and they, who assert that everything is right, do not express themselves correctly; they should say that everything is best.”

Candide listened attentively and believed implicitly, for he thought Miss Cunegund excessively handsome, though he never had the courage to tell her so. He concluded that next to the happiness of being Baron of Thunder-ten-tronckh, the next was that of being Miss Cunegund, the next that of seeing her every day, and the last that of hearing the doctrine of Master Pangloss, the greatest philosopher of the whole province, and consequently of the whole world.

Everything old is new again. What Voltaire was mocking were the glib and facile justifications of injustice in his time, which presume the current state of the world is in its best possible state and everything you see is the result of natural inevitability. Candide in Silicon Valley would exclaim, “Oh Pangloss, why is it that men are so over-represented in tech?” and Pangloss’s response, “For men are better at tech because of their intrinsic personality traits, and in this best of all possible worlds, male personality traits and even their flaws make for the best-possible technology and business practices.”

Anyone who has been following the Uber saga might question Panglossian reasoning about why tech is male. Even if the tech sector, as it exists today, is male-dominated because men perform better in the current pathological and Machiavellian environment, that doesn’t mean this is ideal, that it isn’t hugely, culturally flawed, and maybe desperately in need of womanly empathy. Taking such data at face value, an industry that is blind to the needs of fully half of its customers, or blind to the potential benefit of the perspective of the other half of the population, is playing with fire. Do we really think situations like Uber’s are a coincidence given the toxic masculinity of its leadership? The male-dominated model is not the best of all possible worlds. The male-dominated model was built by men, for men, so why be surprised when less women are attracted to it and fare worse within it.

Other authors have already done some of the heavy lifting, tackling the low scientific credibility of these claims and placing them in the historical context of the usual power-dynamic of trying to scientifically justify the status quo. These are useful, but we can expand upon them and use this essay as a learning opportunity for how to detect pseudoscience, so one hopefully doesn’t have to go through all the effort of endless debunking every time an ideologue vomits up some new dreck to explain why it’s only natural males, or whites, or whomever comes out on top.

And that is one thing we should immediately detect, the similarity to historical “just-so” arguments of scientific racism from the last few centuries. These arguments are old news, as anyone who has read Stephen Jay Gould’s Mismeasure of Man can tell you, and crop up whenever the dominant class in society has to explain why they’re on top without admitting it’s because they pushed everyone else down then pulled the ladder up after themselves. Once you hear people talking about why current race or gender divisions are natural, one should immediately take whatever argument is coming with a massive dose of skepticism. We have heard this nonsense before.

Let’s start with Damore’s words so it’s clear I’m addressing the scientific claims of his argument, contained in the last element of his TL;DR section and supported by the handful of actual scientific citation.

Differences in distributions of traits between men and women may in part explain why we don’t have 50% representation of women in tech and leadership. Discrimination to reach equal representation is unfair, divisive, and bad for business.

Now keep in mind, this is in the context of an 69:31 M:F ratio at Google which is even higher in the engineering at 80:20

Possible non-bias causes of the gender gap in tech
On average, men and women biologically differ in many ways. These differences aren’t just
socially constructed because:
● They’re universal across human cultures
● They often have clear biological causes and links to prenatal testosterone
● Biological males that were castrated at birth and raised as females often still identify
and act like males
● The underlying traits are highly heritable
● They’re exactly what we would predict from an evolutionary psychology perspective

Note, I’m not saying that all men differ from all women in the following ways or that these
differences are “just.” I’m simply stating that the distribution of preferences and abilities of men
and women differ in part due to biological causes and that these differences may explain why
we don’t see equal representation of women in tech and leadership. Many of these differences
are small and there’s significant overlap between men and women, so you can’t say anything
about an individual given these population level distributions.

It’s so nice that he cleared that up about not applying these findings to individuals this is hard to reconcile with the fact he is suggesting the 69:31 ratio or 80:20 engineering ratio at Google is in some meaningful way affected by these differences. Further, each of these statements lacks citation and can not be taken at face value, and I would describe them as either all wrong or grossly oversimplified. While the differences in gendered personality he subsequently describes is consistent within any culture examined, they are not consistent between cultures, which shows these are still culturally-dependent and not purely biologically deterministic (And of course, there is no matriarchal culture for comparison 😉 ) I have no idea why he conflated the research on androgens on personality development using CAH or androgen insensitivity with studies of personality changes in castration related to sex-reassignment, and prostate cancer treatment (if anyone can find a study of those “castrated at birth” please show me as I cant find it – I suspect he’s confused). He mixes two effects by saying androgens in the womb have effects on subsequent personality (likely but difficult to separate from gender norms) but then saying traits are heritable. Which is it? The Y chromosome or exposure to androgens? One is genetic, one is congenital. Finally, it’s rare to find examples where EP is truly “predicting” anything and not just indulging in the just-so stories and adaptationism (my favorite example of an evo-psych just so), i.e. more Panglossian logic. The field is…problematic, and strong statements about EP predictions like “exactly what we would predict from an evolutionary psychology perspective” should set off alarm bells.

Each of these statements are gross simplifications of large bodies of research, some of which are highly problematic areas with reproducibility problems, to justify a 2:1 or even 4:1 difference in hiring of men:women at Google. There is a general rule that “extraordinary claims require extraordinary proof”, well here is a man saying the reason Google has 2-4x as many men as women isn’t just the known, historic, institutional sexism that kept women from voting, owning property, having access to college education, equal pay etc., but fundamental biological differences across all cultures, that exists from birth, programmed by testosterone yet highly heritable (wah?) and conforming to predictions of a controversial scientific field that starts with conclusions and works backward to explanation. These effects are large enough, apparently, that Google should not try for parity in hiring and stop diversity training. Riiight. You better have some rock solid data to back this up.

Let’s look at the extraordinary data on why the women are so terribly disadvantaged based on their biology for software engineering (heads up, it’s a couple of wikipedia articles, and :

Personality differences
Women, on average, have more:

Openness directed towards feelings and aesthetics rather than ideas. Women generally also have a stronger interest in people rather than things, relative to men (also interpreted as empathizing vs. systemizing).
These two differences in part explain why women relatively prefer jobs in social or artistic areas. More men may like coding because it requires systemizing and even within SWEs, comparatively more women work on front end, which deals with both people and aesthetics.
Extraversion expressed as gregariousness rather than assertiveness. Also, higher agreeableness.
This leads to women generally having a harder time negotiating salary, asking for raises, speaking up, and leading. Note that these are just average differences and there’s overlap between men and women, but this is seen solely as a women’s issue. This leads to exclusory programs like Stretch and swaths of men without support.
Neuroticism (higher anxiety, lower stress tolerance).This may contribute to the higher levels of anxiety women report on Googlegeist and to the lower number of women in high stress jobs.
Note that contrary to what a social constructionist would argue, research suggests that “greater nation-level gender equality leads to psychological dissimilarity in men’s and women’s personality traits.” Because as “society becomes more prosperous and more egalitarian, innate dispositional differences between men and women have more space to develop and the gap that exists between men and women in their personality becomes wider.” We need to stop assuming that gender gaps imply sexism.

For this segment he cites the wikipedia page on “sex differences in psychology; personality traits”, only useful for some background, not proof women!=engineers.

He cites This paper, which summarizes meta-analyses in the literature of personality with a reproducible effect showing that in a 6 dimensional model of personality traits women and men consistently score differently on being interested in “persons” vs “things”, and also that these sex differences in behavior are consistent across cultures. To be fair supporting literature exists which correlates these personality trends with differences in vocational choices, so it’s plausible that, all things being equal, there may be a gender gap in some professions based on personality traits.

This may be the only item of interest in his entire paper, as it is reproducible and there is evidence it impacts what choices the different sexes make about jobs. The problem I have with it is there is no way to control for the effect of how humans, starting when we’re toddlers, start to consolidate gender roles. If the image of the engineer or tech industry is predominantly male, this becomes a self-fulfilling prophecy. It also assumes that the current male-dominated status of tech couldn’t benefit from traits on the female axis including better interest in “persons” and creativity/artistic expression. The argument becomes a tautology, men are attracted to the tech sector because the tech sector is male. Add to that the tendency of institutions to maintain homogeneity by effects like in-group bias, and you see why male-dominated fields may remain static. Just imagine if we had accepted similar Panglossian logic 50 years ago that these gender-distributions as some kind of inevitable consequence of natural gender preferences, we’d still have only male doctors, lawyers, and executives, because, this is the best of all possible worlds, and there must be some evolutionary psychology to explain why there are no women doctors, or lawyers, or executives.

Damore then cites the wikipedia article on the Empathizing–systemizing theory. This appears to be moderately central to his argument, but again it is weak evidence. Not to beat a dead horse, but we are once again starting with the assumption that the current state of affairs represents some kind of ideal – the dominance of men in the field is “just so” because they’re more adapted to it, rather than they adapted the field to themselves or that there’s a host of historical factors such as women only got the right to vote in the last 100 years, co-ed schools in the last 50 years, they are still treated as second-class citizens including when it comes to pay. It also accepts one of the authors underlying assumptions, which is outside of my experience, which is that empathy is bad for engineering at Google. I can’t debate that, but least one former Googler has responded to this assertion and says absolutely not:

What I am is an engineer, and I was rather surprised that anyone has managed to make it this far without understanding some very basic points about what the job is. The manifesto talks about making “software engineering more people-oriented with pair programming and more collaboration” but that this is fundamentally limited by “how people-oriented certain roles and Google can be;” and even more surprisingly, it has an entire section titled “de-emphasize empathy,” as one of the proposed solutions.

People who haven’t done engineering, or people who have done just the basics, sometimes think that what engineering looks like is sitting at your computer and hyper-optimizing an inner loop, or cleaning up a class API. We’ve all done this kind of thing, and for many of us (including me) it’s tremendous fun. And when you’re at the novice stages of engineering, this is the large bulk of your work: something straightforward and bounded which can be done right or wrong, and where you can hone your basic skills.

But it’s not a coincidence that job titles at Google switch from numbers to words at a certain point. That’s precisely the point at which you have, in a way, completed your first apprenticeship: you can operate independently without close supervision. And this is the point where you start doing real engineering.

And once you’ve understood the system, and worked out what has to be built, do you retreat to a cave and start writing code? If you’re a hobbyist, yes. If you’re a professional, especially one working on systems that can use terms like “planet-scale” and “carrier-class” without the slightest exaggeration, then you’ll quickly find that the large bulk of your job is about coordinating and cooperating with other groups.

Essentially, engineering is all about cooperation, collaboration, and empathy for both your colleagues and your customers. If someone told you that engineering was a field where you could get away with not dealing with people or feelings, then I’m very sorry to tell you that you have been lied to. Solitary work is something that only happens at the most junior levels, and even then it’s only possible because someone senior to you — most likely your manager — has been putting in long hours to build up the social structures in your group that let you focus on code.

All of these traits which the manifesto described as “female” are the core traits which make someone successful at engineering. Anyone can learn how to write code; hell, by the time someone reaches L7 or so, it’s expected that they have an essentially complete mastery of technique. The truly hard parts about this job are knowing which code to write, building the clear plan of what has to be done in order to achieve which goal, and building the consensus required to make that happen.

Tom Smykowski says, engineers need more empathy

If true, this kind of knocks the teeth out of this particular “just so” justification that empathy is maladaptive. Is it possible, that the current culture of masculinity and therefore insularity is holding tech back? Couldn’t one make just as good an argument here, that Google hasn’t maxed its potential until it harnesses women’s superior social and interpersonal skills to help with things like teamwork and management? Is there no positive side to hiring women? And that is assuming these are large enough difference between women and men on these behavioral traits to justify hiring twice as many men as women.

Take a look at a recent paper from the theorist behind the E-S scale – Simon Baron-Cohen – and the differences on his Autism Spectrum Quotient scores (a newer scale Baron-Cohen has validated from the EQ SQ research and seems to have moved onto) for women vs men and STEM fields vs others that Damore is alluding to (I have to make some leaps here, Damore links the “E-S scale” wikipedia, which is a touch dated, without indicating a specific study, and ostensibly is referring to this work by Baron-Cohen who has advanced the idea of the “male mind” and autism being an excess of male mental traits – this itself has been critiqued as “neurosexist”). Studying an enormous database Baron Cohen finds a statistically-significant difference in AQ score between men and women, and women and those in STEM:

http://ift.tt/2uzSKmy

While this may be statistically significant, it’s still a tiny difference overall a matter of about 3 points on this scale by most measures I’ve read, and indeed STEM workers trend towards a similar 2-3 point higher AQ score. It is also hard to conclude the differences between women’s score and STEM is due to intrinsic or cultural factors – again, the best of all possible worlds fallacy, and it is no evidence to believe that 2-3 points difference in the mean score explains 2-4 fold gaps in hiring of men vs women. Draw a line at about 21 and ballpark an SD, of +/- 8 points, are there 2-4x as many men under the curve right there? Of course not. There’s too much meat under that curve to justify more than a couple of points difference. Alternatively, you could make an argument from the tails, that you could conceive of the extremes of the population such as AQ > 40 having approximately 2x as many men with this trait. One would have to believe that the population at google is so far shifted to the right in terms of male braininess, that the majority of the population at google has a mean AQ beyond 30 or 40. Is this the case? Unlikely, as the nonclinical range of AQ is consistently in the teens to twenties and those diagnosed with autistic spectrum disorder tend to score in the mid 30s.

At the same time that Damore is critical of reducing populations to their means when there is significant overlap, to believe his argument – that tech is segregated by gender because not enough women have the “male mind” described by Baron-Cohen – requires one to believe that the status-quo ratio represents the ideal workforce, that these tiny differences in gender behavior are so debilitating as to explain the 2-4x difference in hiring, and that nothing beneficial is brought to the table by “empathic” team members. This makes no sense, these differences are slight. The area under the curve doesn’t support that these tiny differences – even if they were intensely meaningful, could generate such large differences in hiring. The areas where the variance between the populations becomes larger than the female population size is far above typical scores for ASD. Is the contention that the neurotypical can’t code?

Barely worth mentioning, he alludes to negative female personality traits by including a link to this wikipedia article on Neuroticism. This is a similarly weak argument. Again the effect is meaningless in size, if you go to the primary literature it’s consistent but small. There is no evidence such an mild difference in gender behaviors with regards to neuroticism would result in such a dramatic difference in hiring or performance, nor is it explained why neuroticism would be less adaptive in engineering vs other fields.

Finally he cites this opinion piece dismissing wage gaps between genders from a Libertarian online magazine, ignored without comment.

Does anyone maybe feel already the evidence here is a bit…light? You’re going to tell an entire gender they can’t do engineering based on a 3 psychology papers showing small and likely irrelevant differences in gendered behavior, a couple of wikipedia pages, and a libertarian opinion piece about how the wage gap is imaginary? You are surprised when women read this and they’re pissed? Do those saying this is “science” like David Brooks want to maybe rethink their expertise on this topic? Because they’re not looking too competent right now. This is classic pseudoscience, a weak, cherry-picked literature is flogged to support some ideological nonsense.

Next Damore asks why might men be more suited for software engineering? Well he’s got a whole paragraph and three more “sciencey” citations to justify that:

Men’s higher drive for status
We always ask why we don’t see women in top leadership positions, but we never ask why we
see so many men in these jobs. These positions often require long, stressful hours that may not
be worth it if you want a balanced and fulfilling life.
Status is the primary metric that men are judged on4, pushing many men into these higher
paying, less satisfying jobs for the status that they entail. Note, the same forces that lead men
into high pay/high stress jobs in tech and leadership cause men to take undesirable and
dangerous jobs like coal mining, garbage collection, and firefighting, and suffer 93% of
work-related deaths.

To justify this he cites the Atlantic opinion piece “The War Against Boys” which counter-intuitively suggests women are better at school than boys, and it’s boys whose performance is undermined (and this helps Damore’s argument how?). He cites this paper on gender differences in mate selection criteria, sadly is paywalled but it’s conclusions are college men prefer good looks, and college women want financial success in a mate, therefore men are more competitive for status jobs in order to satisfy female sexual selection. One could point out, this is a gross simplification of human mating dynamics and is one effect among many in human attraction or every woman alive would coo over Donald Trump. Finally he cites this paper on effects of testosterone on college age men that found when injected with additional testosterone in an Ultimatum game they behaved more aggressively, but also more generous to those who made them bigger offers thus supporting the idea testosterone enhances “status seeking” behavior. Again one would have to believe this is a large enough effect that women and men have no interest in tech or engineering for any other reason than mate selection. Or show that those engineers seeking status are running higher testosterone levels than men in other “high status” jobs to show this is anything other than a suggestive result. It is further discredited by the fact that over the last 40 years women have pursued more and more “high status” jobs. Although their numbers are more uneven with regards to “things important” type (read engineering) fields, to say this is biological determinism and not male obstructionism is not justified based on a single testosterone experiment done in college students and a oversimplified view of mate selection. It ignores that women are perfectly capable of being engineers and functioning at the top of fields like physics or mathematics, and human mating behaviors are far more complex than “women are gold-diggers.”

Again. Does anyone here find the evidence here a bit light? David Schmitt seems to agree and his research is that being cited by Damore:

Still, it is not clear to me how such sex differences are relevant to the Google workplace. And even if sex differences in negative emotionality were relevant to occupational performance at Google (e.g., not being able to handle stressful assignments), the size of these negative emotion sex differences is not very large (typically, ranging between “small” to “moderate” in statistical effect size terminology; accounting for perhaps 10% of the variance1). Using someone’s biological sex to essentialize an entire group of people’s personality is like surgically operating with an axe. Not precise enough to do much good, probably will cause a lot of harm. Moreover, men are more emotional than women in certain ways, too. Sex differences in emotion depend on the type of emotion, how it is measured, where it is expressed, when it is expressed, and lots of other contextual factors. How this all fits into the Google workplace is unclear to me. But perhaps it does.

As to sex differences in mate preferences and status-seeking, these topics also have been heavily researched across cultures (for a review, see here). Again, though, most of these sex differences are moderate in size and in my view are unlikely to be all that relevant to the Google workplace (accounting for, perhaps, a few percentage points of the variability between men’s and women’s performance outcomes).

Culturally universal sex differences in personal values and certain cognitive abilities are a bit larger in size (see here), and sex differences in occupational interests are quite large2. It seems likely these culturally universal and biologically-linked sex differences play some role in the gendered hiring patterns of Google employees. For instance, in 2013, 18% of bachelor’s degrees in computing were earned by women, and about 20% of Google technological jobs are currently held by women. Whatever affirmative action procedures Google is using appear to be working pretty well (at least at the tech job level). Still, I think it’s important to keep in mind that most psychological sex differences are only small to moderate in size, and rather than grouping men and women into dichotomous groups, I think sex and sex differences are best thought of scientifically as multidimensional dials, anyway (see here).

Not exactly a ringing endorsement of Damore’s use of his research and the data on increasing “status” vs “things” jobs suggests women might have been settling for those jobs only as they were in enforced gendered roles. Schmitt also seems to agree, extraordinary claims require extraordinary evidence, and these effects are small. Linking gendered behavioral differences to massive differences in performance in tech or engineering is an enormous stretch of logic. Schmitt emphasizes uncertainty, and the need to recognize complex role of gender on human behavior, he sure sounds like a scientist (for an Evolutionary Psychologist 😉 ).

The one who doesn’t sound like a scientist is Damore, who it turns out falsely claimed to have a PhD, gave his first interviews to alt-right youtubers, compared Google to Soviet prison labor camps even wearing a “Goolag” shirt for his WSJ editorial. He sounds less like a scientist, and more like he’s read the Crank Howto. I don’t understand how he ever expected to keep his job, after it turns out he did not have a PhD, he blasted a crank manifesto at his workplace that demeans a significant portion of the Google workforce, managed to embarrass his company on a national level, and ultimately demonstrated fundamental incompetencies in analysis and workplace etiquette. He would probably benefit from some training along the empathy axis, but instead is nursing a google-sized persecution complex.

To summarize, a junior, not-PhD employee of Google has written a 10 page document which purports to explain that the massive imbalance in male:female ratio at the company is not necessarily due to historic struggles of women for equal representation in equality, readily measurable bias, or structural sexism, but is instead due to female biology. The evidentiary basis for this argument is 3 bullet points followed by 3 short paragraphs that cite a few wikipedia pages, some libertarian/rightwing opinion pieces, a handful of papers on gendered differences in behavior showing some interesting but small differences between men and women, a bizarre reference to data from males castrated at birth (please someone find me that paper), some handwaving about male/female sex selection and “status” belied by a 40 year trend in women increasingly taking higher status jobs, and a borderline sexist psychological theory about “masculine brains” with similarly small differences between men and women. Notably, all of his arguments are dependent on the assumption that the male brain is fundamentally better at engineering because they got these jobs first and are thus appropriately over represented, and qualities like empathy and interpersonal skills don’t contribute to what is already a flawlessly healthy corporate culture in tech. By this logic women don’t do well in this culture because female cognition is inadequate to the task, not because it’s hard to fit in as a woman in at the boys club.

http://ift.tt/2uzKWkN

He does not discuss or cite any of the extensive literature for the constant measurable bias women undergo in the workplace. His argument dismisses the more probable negative effects of historical oppression of women (denial of the vote, of property, of jobs, of education) well into the last century as well as ongoing structural sexism. He fails to link these effects to actual performance or interest in software engineering, he grossly oversimplifies the relationship between culture and behavior in favor of radical biological determinism, and wraps it into a typical Panglossian “just-so” story.

After predictably being fired for sending a crudely-argued, c-grade essay on why “girls like talking not math”, he has now made the rounds of the alt-right internet, the antediluvian editorial page of the WSJ, and has cried persecution at Google comparing himself to a slave laborer. He denies he’s an ideologue, even though as example of left wing denialism he cites John Tierney of the Manhattan Institute, and his argument that global warming scientists are the real threat to science (plus Rachel Carson DDT revisionism – yay!). By their fruits you shall know them.

What this shows is, the people who are impressed by his line of argumentation and series of events are ideologically-primed to accept it, not that they are particularly good judges of science. Pay attention to who buys into this uncritically, it’s better evidence for weak, sexist minds than it is for weak minds of a sex.



from ScienceBlogs http://ift.tt/2fCVU2a